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CAS 110483-43-7

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Uridine, 2′-bromo-2′-deoxy-5-methyl-, 3′,5′-diacetate

Description:
Uridine, 2′-bromo-2′-deoxy-5-methyl-, 3′,5′-diacetate, with the CAS number 110483-43-7, is a modified nucleoside derivative. This compound features a uridine backbone, which is a nucleoside composed of a ribose sugar and a uracil base, but with specific modifications that enhance its chemical properties and biological activity. The presence of a bromo group at the 2′ position and methyl substitution at the 5′ position alters its reactivity and potential interactions with biological molecules. Additionally, the diacetate groups at the 3′ and 5′ positions contribute to its stability and solubility, making it suitable for various biochemical applications. Such modifications can influence its role in nucleic acid synthesis, cellular uptake, and potential therapeutic uses. Overall, this compound exemplifies the diverse structural variations in nucleosides that can lead to significant differences in their chemical behavior and biological functions.
Formula:C14H17BrN2O7
InChI:InChI=1/C14H17BrN2O7/c1-6-4-17(14(21)16-12(6)20)13-10(15)11(23-8(3)19)9(24-13)5-22-7(2)18/h4,9-11,13H,5H2,1-3H3,(H,16,20,21)/t9-,10?,11-,13-/m1/s1
InChI key:InChIKey=LIZACCKAVBPBPQ-PRULPYPASA-N
SMILES:Br[C@H]1[C@@H](O[C@H](COC(C)=O)[C@H]1OC(C)=O)N2C(=O)NC(=O)C(C)=C2
Synonyms:
  • Uridine, 2′-bromo-2′-deoxy-5-methyl-, 3′,5′-diacetate
  • 2′-Bromo-2′-deoxy-3′,5′-di-O-acetyl-5-methyluridine
  • 3',5'-Di-O-acetyl-2'-broMo-2'-deoxy-5-Methyluridine
  • 2'-Bromo-2'-deoxy-3',5'-di-O-acetyl-5-methyluridine
  • Uridine, 2'-bromo-2'-deoxy-5-methyl-, 3',5'-diacetate
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  • 2-Bromo-2-deoxy-5-methyluridine-3,5-diacetate
    Biosynth
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    2-Bromo-2-deoxy-5-methyluridine-3,5-diacetate

    CAS:
    <p>2-Bromo-2-deoxy-5-methyluridine-3,5-diacetate is a novel synthetic nucleoside analogue. It has been shown to inhibit the proliferation of cancer cells and have antiviral activity. It is phosphorylated by kinase enzymes to form 2'-bromo-2'-deoxyuridine monophosphate (BrDUMP). This compound also inhibits DNA replication, RNA transcription, and protein synthesis.</p>
    Purity:Min. 95%

    Ref: 3D-NB02564

    1g
    2,440.00€