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CAS 110536-31-7

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22-fluorovitamin D3

Description:
22-Fluorovitamin D3, also known by its CAS number 110536-31-7, is a synthetic derivative of vitamin D3 (cholecalciferol) that has been modified to include a fluorine atom at the 22nd carbon position. This modification alters its biological activity and pharmacokinetics compared to natural vitamin D3. The presence of the fluorine atom enhances its stability and may influence its interaction with vitamin D receptors, potentially leading to different metabolic effects. Like other vitamin D analogs, 22-fluorovitamin D3 plays a role in calcium and phosphate homeostasis, which is crucial for bone health. It is often studied for its potential therapeutic applications in conditions related to vitamin D deficiency, such as osteoporosis and certain autoimmune diseases. The compound is typically characterized by its molecular structure, solubility in organic solvents, and specific spectral properties, which can be analyzed using techniques such as NMR and mass spectrometry. Overall, 22-fluorovitamin D3 represents an important area of research in the field of endocrinology and pharmacology.
Formula:C27H43FO
InChI:InChI=1/C27H43FO/c1-18(2)8-15-26(28)20(4)24-13-14-25-21(7-6-16-27(24,25)5)10-11-22-17-23(29)12-9-19(22)3/h10-11,18,20,23-26,29H,3,6-9,12-17H2,1-2,4-5H3/b21-10+,22-11-/t20-,23+,24+,25-,26?,27+/m0/s1
Synonyms:
  • 9,10-Secocholesta-5,7,10(19)-trien-3-ol, 22-fluoro-, (3beta,5Z,7E)-
  • (3R,5Z,7E)-22-fluoro-9,10-secocholesta-5,7,10-trien-3-ol
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  • 22-Fluorovitamin D3

    CAS:
    22-Fluorovitamin D3 is a synthetic analog of vitamin D3, which is derived from chemical synthesis involving fluorination at the C-22 position. This modification results in a compound that mimics the structure and activity of naturally occurring vitamin D3 but with altered pharmacokinetics and metabolic stability. The fluorine atom, due to its size and electronegativity, influences the binding affinity and activity of the compound at vitamin D receptors.
    Formula:C27H43FO
    Purity:Min. 95%
    Molecular weight:402.63 g/mol

    Ref: 3D-FF77293

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