CAS 110558-69-5

Pregna-1,4-diene-3,11,20-trione, 21-(fluoro-18F)-17-hydroxy-

Description:

Pregna-1,4-diene-3,11,20-trione, 21-(fluoro-18F)-17-hydroxy- is a synthetic steroid compound that incorporates a fluorine isotope, specifically fluorine-18, which is commonly used in positron emission tomography (PET) imaging. This compound is characterized by its steroid backbone, which includes a series of functional groups such as hydroxyl and keto groups, contributing to its biological activity. The presence of the fluorine-18 isotope allows for its visualization in medical imaging, making it valuable in the diagnosis and monitoring of various conditions, particularly in oncology. The compound's structure suggests potential interactions with steroid receptors, which may influence its pharmacological properties. Additionally, the stability and reactivity of the fluorinated compound can vary based on its environment and formulation, impacting its efficacy and safety profile in clinical applications. Overall, this compound exemplifies the intersection of organic chemistry and medicinal applications, particularly in the field of radiopharmaceuticals.

Formula: C₂₁H₂₅FO₄

InChI: InChI=1S/C21H25FO4/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h5,7,9,14-15,18,26H,3-4,6,8,10-11H2,1-2H3/t14-,15-,18+,19-,20-,21-/m0/s1/i22-1

InChI key: InChIKey=QQWLPAPHNPKYGT-JHZVGIEFSA-N

SMILES: C[C@@]12[C@]([C@]3([C@@]([C@]4(C)C(CC3)=CC(=O)C=C4)(C(=O)C1)[H])[H])(CC[C@@]2(C(C[18F])=O)O)[H]

Synonyms:

• 21-(Fluoro-18F)-17-hydroxypregna-1,4-diene-3,11,20-trione
• 21-(~18~F)fluoro-17-hydroxypregna-1,4-diene-3,11,20-trione
• 21-[¹⁸F]Fluoroprednisone
• Pregna-1,4-diene-3,11,20-trione, 21-(fluoro-18F)-17-hydroxy-
• Pregna-1,4-diene-3,11,20-trione, 21-(fluoro-¹⁸F)-17-hydroxy-
• 21-[18F]Fluoroprednisone
• 21-Fluoroprednisone