CAS 110588-57-3

Saperconazole

Description:

Saperconazole is an antifungal agent primarily used in the treatment of various fungal infections. It belongs to the class of compounds known as azoles, which function by inhibiting the synthesis of ergosterol, an essential component of fungal cell membranes. This mechanism disrupts the integrity of the cell membrane, leading to cell death. Saperconazole exhibits broad-spectrum antifungal activity, making it effective against a range of dermatophytes and yeast infections. The compound is typically administered topically, and its formulation may include various excipients to enhance skin penetration and stability. In terms of physical properties, Saperconazole is generally characterized by its solubility in organic solvents and limited solubility in water, which is common among azole derivatives. Safety and efficacy profiles are established through clinical studies, and like other antifungal agents, it may have potential side effects, including skin irritation or allergic reactions. Overall, Saperconazole represents a valuable option in the antifungal therapeutic arsenal, particularly for dermatological applications.

Formula: C₃₅H₃₈F₂N₈O₄

InChI: InChI=1/C35H38F2N8O4/c1-3-25(2)45-34(46)44(24-40-45)29-7-5-27(6-8-29)41-14-16-42(17-15-41)28-9-11-30(12-10-28)47-19-31-20-48-35(49-31,21-43-23-38-22-39-43)32-13-4-26(36)18-33(32)37/h4-13,18,22-25,31H,3,14-17,19-21H2,1-2H3/t25?,31-,35-/m0/s1

SMILES: CCC(C)n1c(=O)n(cn1)c1ccc(cc1)N1CCN(CC1)c1ccc(cc1)OC[C@H]1CO[C@](Cn2cncn2)(c2ccc(cc2F)F)O1

Synonyms:

• Saperconazole [USAN:INN:BAN]
• (+-)-1-sec-Butyl-4-(p-(4-(p-(((2R*,4S*)-2-(2,4-difluorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl)methoxy)phenyl)-1-piperazinyl)phenyl)-delta(sup 2)-1,2,4-triazolin-5-one
• 3H-1,2,4-Triazol-3-one, 4-(4-(4-(4-((2-(2,4-difluorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl)methoxy)phenyl)-1-piperazinyl)phenyl)-2,4-dihydro-2-(1-methylpropyl)-
• R66905
• Saperconazol
• Saperconazol [INN-Spanish]
• Saperconazolum
• Saperconazolum [INN-Latin]
• 2-(butan-2-yl)-4-{4-[4-(4-{[(2S,4R)-2-(2,4-difluorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin-1-yl]phenyl}-2,4-dihydro-3H-1,2,4-triazol-3-one
• 2-(butan-2-yl)-4-{4-[4-(4-{[(2R,4S)-2-(2,4-difluorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin-1-yl]phenyl}-2,4-dihydro-3H-1,2,4-triazol-3-one

Saperconazole

CAS: 110588-57-3

Formula: C₃₅H₃₈F₂N₈O₄

Purity: 99.35%

Color and Shape: Solid

Molecular weight: 672.7242

Ref: IN-DA008RLP

Saperconazole

Controlled Product

CAS: 110588-57-3

Formula: C₃₅H₃₈F₂N₈O₄

Color and Shape: Neat

Molecular weight: 672.724

Ref: TR-S159270

Saperconazole

CAS: 110588-57-3

Saperconazole is a broad-spectrum antifungal triazole (MIC90: 0.19 mg/L).

Formula: C₃₅H₃₈F₂N₈O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 672.72

Ref: TM-T16714