CAS 1106-03-2

17,21-dihydroxy-16β-methylpregna-1,4-diene-3,11,20-trione 21-acetate

Description:

The chemical substance known as 17,21-dihydroxy-16β-methylpregna-1,4-diene-3,11,20-trione 21-acetate, with the CAS number 1106-03-2, is a synthetic steroid and a derivative of the natural hormone progesterone. It exhibits potent anti-inflammatory and immunosuppressive properties, making it useful in various medical applications, particularly in the treatment of conditions such as autoimmune disorders and allergies. This compound is characterized by its steroidal structure, which includes multiple fused rings typical of steroid hormones, and specific functional groups that contribute to its biological activity. The presence of hydroxyl groups enhances its solubility and reactivity, while the acetate moiety can influence its pharmacokinetics. As a glucocorticoid, it interacts with glucocorticoid receptors, modulating gene expression and affecting cellular responses. Its therapeutic use is often accompanied by a careful consideration of potential side effects, including metabolic changes and impacts on the endocrine system. Overall, this compound exemplifies the complexity and utility of synthetic steroids in modern medicine.

Formula: C₂₄H₃₀O₆

InChI: InChI=1/C24H30O6/c1-13-9-18-17-6-5-15-10-16(26)7-8-22(15,3)21(17)19(27)11-23(18,4)24(13,29)20(28)12-30-14(2)25/h7-8,10,13,17-18,21,29H,5-6,9,11-12H2,1-4H3/t13-,17-,18-,21+,22-,23-,24-/m0/s1

InChI key: InChIKey=RZAMUHXEOMZXET-ABQXZQTJSA-N

SMILES: C[C@@]12[C@]([C@]3([C@](C(=O)C1)([C@]4(C)C(CC3)=CC(=O)C=C4)[H])[H])(C[C@H](C)[C@@]2(C(COC(C)=O)=O)O)[H]

Synonyms:

• (16Beta)-17-Hydroxy-16-Methyl-3,11,20-Trioxopregna-1,4-Dien-21-Yl Acetate
• (16β)-21-(Acetyloxy)-17-hydroxy-16-methylpregna-1,4-diene-3,11,20-trione
• 16-Meprednisone acetate
• 17,21-Dihydroxy-16beta-methylpregna-1,4-diene-3,11,20-trione 21-acetate
• Pregna-1,4-diene-3,11,20-trione, 17,21-dihydroxy-16β-methyl-, 21-acetate
• Pregna-1,4-diene-3,11,20-trione, 21-(acetyloxy)-17-hydroxy-16-methyl-, (16β)-
• [2-[(8S,9S,10R,13S,14S,16S,17R)-17-hydroxy-10,13,16-trimethyl-3,11-dioxo-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate
• 17,21-Dihydroxy-16β-Methyl-pregna-1,4-diene-3,11,20-trione 21-Acetate
• 21-Acetyloxy-17-hydroxy-16β-methylpregna-1,4-diene-3,11,20-trione
• (16β)-21-(Acetyloxy)-17-hydroxy-16-Methyl-pregna-1,4-diene-3,11,20-trione
• [2-[(8S,9S,10R,13S,14S,16S,17R)-17-hydroxy-10,13,16-trimethyl-3,11-dioxo-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxo-ethyl] ethanoate
• Meprednisone 21-Acetate