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CAS 1107-99-9

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Prednisolone pivalate

Description:
Prednisolone pivalate is a synthetic corticosteroid with anti-inflammatory and immunosuppressive properties. It is derived from prednisolone, a well-known glucocorticoid, and is characterized by the addition of a pivalate ester group, which enhances its lipophilicity and alters its pharmacokinetic profile. This modification allows for improved absorption and prolonged action in the body. Prednisolone pivalate is typically administered via intramuscular injection and is used in the treatment of various inflammatory and autoimmune conditions, including allergies, asthma, and certain skin disorders. The compound exhibits a range of biological activities, including the inhibition of inflammatory mediators and modulation of immune responses. Its therapeutic effects are often accompanied by potential side effects, which may include weight gain, mood changes, and increased susceptibility to infections. As with other corticosteroids, careful monitoring is essential during treatment to mitigate adverse effects and ensure optimal therapeutic outcomes.
Formula:C26H36O6
InChI:InChI=1S/C26H36O6/c1-23(2,3)22(30)32-14-20(29)26(31)11-9-18-17-7-6-15-12-16(27)8-10-24(15,4)21(17)19(28)13-25(18,26)5/h8,10,12,17-19,21,28,31H,6-7,9,11,13-14H2,1-5H3/t17-,18-,19-,21+,24-,25-,26-/m0/s1
InChI key:InChIKey=PHEOVVDXTQVHAZ-XDANTLIUSA-N
SMILES:C[C@@]12[C@@]3([C@]([C@]4([C@](C)(C[C@@H]3O)[C@](C(COC(C(C)(C)C)=O)=O)(O)CC4)[H])(CCC1=CC(=O)C=C2)[H])[H]
Synonyms:
  • (11Beta)-11,17-Dihydroxy-3,20-Dioxopregna-1,4-Dien-21-Yl 2,2-Dimethylpropanoate
  • (11β)-21-(2,2-Dimethyl-1-oxopropoxy)-11,17-dihydroxypregna-1,4-diene-3,20-dione
  • 11,17-Dihydroxy-3,20-Dioxopregna-1,4-Dien-21-Yl 2,2-Dimethylpropanoate
  • 11β,17α-Dihydroxy-21-pivaloyloxypregna-1,4-diene-3,20-dione
  • Mecortolon
  • Prednisolone 21-trimethylacetate
  • Prednisolone Pivalate
  • Prednisolone trimethylacetate
  • Pregna-1,4-diene-3,20-dione, 11β,17,21-trihydroxy-, 21-pivalate
  • Pregna-1,4-diene-3,20-dione, 21-(2,2-dimethyl-1-oxopropoxy)-11,17-dihydroxy-, (11β)-
  • See more synonyms
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