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CAS 110703-94-1

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Zopolrestat

Description:
Zopolrestat is a chemical compound primarily recognized for its role as an aldose reductase inhibitor, which is significant in the management of diabetic complications. It is characterized by its ability to inhibit the enzyme aldose reductase, thereby reducing the conversion of glucose to sorbitol, a process implicated in diabetic neuropathy and other complications. The molecular structure of Zopolrestat includes specific functional groups that contribute to its inhibitory activity, making it a subject of interest in pharmacological research. Its efficacy and safety profile have been evaluated in various studies, highlighting its potential therapeutic applications. Additionally, Zopolrestat's solubility, stability, and interaction with biological systems are critical factors that influence its pharmacokinetics and pharmacodynamics. As with many pharmaceutical compounds, understanding its characteristics is essential for optimizing its use in clinical settings and for further development in treating diabetes-related conditions.
Formula:C19H12F3N3O3S
InChI:InChI=1/C19H12F3N3O3S/c20-19(21,22)10-5-6-15-14(7-10)23-16(29-15)9-25-18(28)12-4-2-1-3-11(12)13(24-25)8-17(26)27/h1-7H,8-9H2,(H,26,27)
SMILES:c1ccc2c(c1)c(CC(=O)O)nn(Cc1nc3cc(ccc3s1)C(F)(F)F)c2=O
Synonyms:
  • Zopolrestat [USAN:INN:BAN]
  • 1-Phthalazineacetic acid, 3,4-dihydro-4-oxo-3-((5-(trifluoromethyl)-2-benzothiazolyl)methyl)-
  • 3,4-Dihydro-4-oxo-3-((5-(trifluoromethyl)-2-benzothiazolyl)methyl)-1-phthalazineacetic acid
  • Cp 73850
  • Unii-1Pv3S9Wp3D
  • Zopolrestatum
  • Zopolrestatum [INN-Latin]
  • (4-Oxo-3-{[5-(Trifluoromethyl)-1,3-Benzothiazol-2-Yl]Methyl}-3,4-Dihydrophthalazin-1-Yl)Acetic Acid
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Found 4 products.