CAS 11072-93-8

B-escin

Description:

B-escin, also known as beta-escin, is a triterpenoid saponin derived from the seeds of the horse chestnut tree (Aesculus hippocastanum). It is characterized by its complex structure, which includes a steroid-like backbone and sugar moieties. B-escin exhibits various pharmacological properties, including anti-inflammatory, venotonic, and antioxidant effects, making it useful in treating conditions like chronic venous insufficiency and hemorrhoids. The compound works by enhancing capillary permeability and reducing edema, which contributes to its therapeutic applications. Additionally, B-escin has been studied for its potential to improve microcirculation and promote lymphatic drainage. Its safety profile is generally favorable, although it may cause gastrointestinal disturbances in some individuals. As a saponin, B-escin can also exhibit surfactant properties, influencing its behavior in biological systems. Overall, B-escin is a significant compound in herbal medicine and pharmacology, with ongoing research exploring its broader therapeutic potential.

Formula: C₅₅H₈₆O₂₄

InChI: InChI=1/C55H86O24/c1-10-23(2)46(71)79-43-44(72-24(3)60)55(22-59)26(17-50(43,4)5)25-11-12-30-51(6)15-14-32(52(7,21-58)29(51)13-16-53(30,8)54(25,9)18-31(55)61)75-49-41(77-48-38(67)36(65)34(63)28(20-57)74-48)39(68)40(42(78-49)45(69)70)76-47-37(66)35(64)33(62)27(19-56)73-47/h10-11,26-44,47-49,56-59,61-68H,12-22H2,1-9H3,(H,69,70)/b23-10+/t26?,27-,28-,29?,30?,31-,32?,33-,34-,35+,36+,37-,38-,39+,40+,41-,42+,43?,44+,47+,48-,49-,51?,52-,53?,54-,55?/m1/s1

Synonyms:

• (2S,3S,4S,5R,6R)-6-[[(3S,4S,6aR,6bS,8R,8aR,9R,10R,14bR)-9-acetoxy-8-hydroxy-4,8a-bis(hydroxymethyl)-4,6a,6b,11,11,14b-hexamethyl-10-[(E)-2-methylbut-2-enoyl]oxy-1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicen-3-yl]oxy]-4-hydroxy-3,5-bis[[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy]tetrahydropyran-2-carboxylic acid
• (5ξ,8ξ,9ξ,10ξ,16α,17ξ,18ξ,22α)-22-(acetyloxy)-16,24,28-trihydroxy-21-{[(2E)-2-methylbut-2-enoyl]oxy}olean-12-en-3-yl α-D-glucopyranosyl-(1->2)-[β-D-glucopyranosyl-(1->4)]-β-D-glucopyranosiduronic acid
• Flogencyl
• beta-Aescin
• beta-Aescinu
• beta-Aescinu [Czech]
• beta-Aescusan
• beta-Escin
• beta-Reparil
• β-Aescin
• β-Escin
• Escin (beta-Escin)
• ESCIN, MIXTURE OF SAPONINS OF THE SEED OF AESCULUS HIPPOCASTANUM THE SEED
• b-Aescin crystalline
• Escin (1249202)
• Escin (350 mg)
• ESCIN IIB; AESCIN IIB

Escin

CAS: 11072-93-8

Other glycosides, natural or reproduced by synthesis, and their salts, ethers, esters and other derivatives

Formula: C₅₅H₈₆O₂₄

Color and Shape: White Yellow Crystalline Powder

Molecular weight: 1130.5509

Ref: 45-1249202

β-Escin

CAS: 11072-93-8

Formula: C₅₅H₈₆O₂₄

Purity: 103%

Color and Shape: Solid

Molecular weight: 1131.2569

Ref: IN-DA008RIE

β-Escin

CAS: 11072-93-8

β-Escin

Purity: ≥95%

Molecular weight: 1131.3g/mol

Ref: 54-BUP17290

β-Escin

CAS: 11072-93-8

beta-Escin is a natural mixture of triterpenoid saponins, can be used as a vasoprotective anti-inflammatory, anti-edematous and anti-nociceptive agent.

Formula: C₅₅H₈₆O₂₄

Purity: 96.4% - 98.66%

Color and Shape: White Powder

Molecular weight: 1131.3

Ref: TM-T8846

β-Aescin

CAS: 11072-93-8

β-Aescin is a saponin glycoside, which is derived from the seeds of the horse chestnut tree (Aesculus hippocastanum). It acts primarily through anti-inflammatory mechanisms and improves vascular permeability. By inhibiting enzymes such as hyaluronidase and elastase, β-Aescin reduces the breakdown of glycosaminoglycans and supports capillary integrity. This results in decreased edema and improved venous tone, making it beneficial in reducing symptoms associated with chronic venous insufficiency.

Formula: C₅₅H₈₆O₂₄

Purity: Min. 95%

Color and Shape: White To Off-White Solid

Molecular weight: 1,131.26 g/mol

Ref: 3D-OA10870