CAS 110782-31-5: 2'-O-methyladenosine-ce phosphoramidite for abi

Description: 2'-O-methyladenosine-5'-phosphoramidite is a modified nucleoside analog commonly used in the synthesis of RNA oligonucleotides. This compound features a 2'-O-methyl group on the ribose sugar, which enhances the stability and binding affinity of the RNA strand, making it particularly useful in therapeutic and research applications. The phosphoramidite moiety allows for efficient coupling during solid-phase oligonucleotide synthesis, facilitating the incorporation of this modified nucleotide into RNA sequences. The presence of the methyl group at the 2' position helps to protect the RNA from degradation by nucleases, thereby increasing its half-life in biological systems. This modification can also influence the secondary and tertiary structures of RNA, potentially affecting its function in various biological processes. Overall, 2'-O-methyladenosine-5'-phosphoramidite is a valuable tool in molecular biology, particularly in the development of RNA-based therapeutics and in the study of RNA structure and function.

Formula: C₄₈H₅₄N₇O₈P

Synonyms:

• Ac-dA Phosphoramidite
• 2'-OMe-Bz-A Phosphoramidite
• 2'-O-Methyl-Ra(N-Bz)Phosphoramidite
• 2'-O-Methyl-N6-Benzoyl-5'-O-DMT-Adenosine-3'-CE-Phosphoramidite
• DMT-2'-OMe-A(Bz)-CE-Phosphoramidite
• DMT-2-O-ME-A-CE Phosphoramidite

2’-O-Methyl-rA(N-Bz)phosphoramidite

CAS: 110782-31-5

• Formula: C₄₈H₅₄N₇O₈P
• Purity: 97%
• Color and Shape: Solid
• Molecular weight: 887.9582

5''-O-DMT-2''-O-Me-A(bz) phosphoramidite

CAS: 110782-31-5

(2R,3R,4R,5R)-5-(6-Benzamido-9H-Purin-9-Yl)-2-((Bis(4-Methoxyphenyl)(Phenyl)Methoxy)Methyl)-4-Methoxytetrahydrofuran-3-Yl (2-Cyanoethyl) Diisopropylphosphoramidite

CAS: 110782-31-5

• Purity: 98%
• Molecular weight: 887.96g/mol

DMT-2'-O-methyl-rA(Bz) Phosphoramidite

CAS: 110782-31-5

• Formula: C₄₈H₅₄N₇O₈P
• Purity: >98.0%(HPLC)
• Color and Shape: White to Light yellow powder to crystal
• Molecular weight: 887.97

2'-OMe-A(Bz) Phosphoramidite

CAS: 110782-31-5

• Molecular weight: 887.975

2'-OMe-A(Bz) Phosphoramidite

CAS: 110782-31-5

2’-OMe-A(Bz) Phosphoramidite is a modified phosphoramidite monomer, which can be used for the oligonucleotide synthesis.

• Formula: C₄₈H₅₄N₇O₈P
• Color and Shape: Liquid
• Molecular weight: 887.96

(2R,3R,4R,5R)-5-(6-Benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-methoxytetrahydrofuran-3-yl (2-Cyanoethyl) Diisopropylphosphoramidite

CAS: 110782-31-5

Applications (2R,3R,4R,5R)-5-(6-Benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite is a nucleotide used in the synthesis of native-like crosslinked duplex …

• Formula: C₄₈H₅₄N₇O₈P
• Color and Shape: Neat
• Molecular weight: 887.98

N6-Benzoyl-5'-O-DMT-2'-O-methyladenosine 3'-CE phosphoramidite

CAS: 110782-31-5

N6-Benzoyl-5'-O-DMT-2'-O-methyladenosine 3'-CE phosphoramidite is a nucleoside phosphoramidite used as a building block in the chemical …

• Formula: C₄₈H₅₄N₇O₈P
• Purity: Min. 98 Area-%
• Color and Shape: White Off-White Powder
• Molecular weight: 887.98 g/mol