CAS 110782-31-5
:2'-O-methyladenosine-ce phosphoramidite for abi
Description:
2'-O-methyladenosine-5'-phosphoramidite is a modified nucleoside analog commonly used in the synthesis of RNA oligonucleotides. This compound features a 2'-O-methyl group on the ribose sugar, which enhances the stability and binding affinity of the RNA strand, making it particularly useful in therapeutic and research applications. The phosphoramidite moiety allows for efficient coupling during solid-phase oligonucleotide synthesis, facilitating the incorporation of this modified nucleotide into RNA sequences. The presence of the methyl group at the 2' position helps to protect the RNA from degradation by nucleases, thereby increasing its half-life in biological systems. This modification can also influence the secondary and tertiary structures of RNA, potentially affecting its function in various biological processes. Overall, 2'-O-methyladenosine-5'-phosphoramidite is a valuable tool in molecular biology, particularly in the development of RNA-based therapeutics and in the study of RNA structure and function.
Formula:C48H54N7O8P
Synonyms:- Ac-dA Phosphoramidite
- 2'-OMe-Bz-A Phosphoramidite
- 2'-O-Methyl-Ra(N-Bz)Phosphoramidite
- 2'-O-Methyl-N6-Benzoyl-5'-O-DMT-Adenosine-3'-CE-Phosphoramidite
- DMT-2'-OMe-A(Bz)-CE-Phosphoramidite
- DMT-2-O-ME-A-CE Phosphoramidite
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Found 9 products.
2’-O-Methyl-rA(N-Bz)phosphoramidite
CAS:Formula:C48H54N7O8PPurity:97%Color and Shape:SolidMolecular weight:887.9582Ref: IN-DA007U61
1g56.00€5g120.00€10g178.00€1kgTo inquire25g297.00€50g703.00€100gTo inquire100mg25.00€250mg24.00€(2R,3R,4R,5R)-5-(6-Benzamido-9H-Purin-9-Yl)-2-((Bis(4-Methoxyphenyl)(Phenyl)Methoxy)Methyl)-4-Methoxytetrahydrofuran-3-Yl (2-Cyanoethyl) Diisopropylphosphoramidite
CAS:(2R,3R,4R,5R)-5-(6-Benzamido-9H-Purin-9-Yl)-2-((Bis(4-Methoxyphenyl)(Phenyl)Methoxy)Methyl)-4-Methoxytetrahydrofuran-3-Yl (2-Cyanoethyl) DiisopropylphosphoramiditePurity:98%Molecular weight:887.96g/molDMT-2'-O-methyl-rA(Bz) Phosphoramidite
CAS:Formula:C48H54N7O8PPurity:>98.0%(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:887.972'-OMe-A(Bz) Phosphoramidite
CAS:2’-OMe-A(Bz) Phosphoramidite is a modified phosphoramidite monomer, which can be used for the oligonucleotide synthesis.Formula:C48H54N7O8PColor and Shape:SolidMolecular weight:887.96(2R,3R,4R,5R)-5-(6-Benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-methoxytetrahydrofuran-3-yl (2-Cyanoethyl) Diisopropylphosphoramidite
CAS:Controlled Product<p>Applications (2R,3R,4R,5R)-5-(6-Benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite is a nucleotide used in the synthesis of native-like crosslinked duplex RNA.<br>References Onizuka, K.; et al.: Bioorg. Med. Chem., 25, 2191 (2017).<br></p>Formula:C48H54N7O8PColor and Shape:NeatMolecular weight:887.98N6-Benzoyl-5'-O-DMT-2'-O-methyladenosine 3'-CE phosphoramidite
CAS:<p>N6-Benzoyl-5'-O-DMT-2'-O-methyladenosine 3'-CE phosphoramidite is a nucleoside phosphoramidite used as a building block in the chemical synthesis of oligonucleotides containing a 2’-O-methyl adenosine nucleoside unit. The use of a chemical synthesis rather than an enzymatic one allows oligonucleotides of a desired sequence to be produced. 3’-Cyanoethyl phosphoramidites are typically used by substitution of the di-isopropylamine group with an appropriate alcohol in the presence of an azole catalyst. Oligonucleotides containing 2'-O-methylribonucleoside units have shown site-specific cleavage with E. coli RNase H, either at a hairpin loop or at a stem region.</p>Formula:C48H54N7O8PPurity:Min. 98 Area-%Color and Shape:White Off-White PowderMolecular weight:887.98 g/mol
