CAS 11079-53-1

Hyperforin

Description:

Hyperforin is a naturally occurring polyphenolic compound primarily found in the plant Hypericum perforatum, commonly known as St. John's Wort. It is recognized for its role as a bioactive constituent, contributing to the plant's medicinal properties, particularly in the treatment of mild to moderate depression. Hyperforin exhibits a complex structure, characterized by a fused bicyclic system and multiple functional groups, which contribute to its pharmacological effects. It is known to act as a selective serotonin and norepinephrine reuptake inhibitor, enhancing neurotransmitter levels in the brain. Additionally, hyperforin possesses anti-inflammatory and antimicrobial properties, making it of interest in various therapeutic applications. The compound is lipophilic, which influences its absorption and bioavailability in the body. Hyperforin's stability can be affected by factors such as light and pH, necessitating careful handling and storage. Overall, hyperforin is a significant compound in herbal medicine, with ongoing research exploring its full potential and mechanisms of action.

Formula: C₃₅H₅₂O₄

InChI: InChI=1/C35H52O4/c1-22(2)13-12-19-33(11)27(16-14-23(3)4)21-34(20-18-25(7)8)30(37)28(17-15-24(5)6)31(38)35(33,32(34)39)29(36)26(9)10/h13-15,18,26-27,37H,12,16-17,19-21H2,1-11H3/t27-,33+,34+,35-/m0/s1

InChI key: InChIKey=IWBJJCOKGLUQIZ-HQKKAZOISA-N

SMILES: C(C(C)C)(=O)[C@@]12[C@@](CCC=C(C)C)(C)[C@@H](CC=C(C)C)C[C@@](CC=C(C)C)(C1=O)C(=O)C(CC=C(C)C)=C2O

Synonyms:

• (1R,5R,7S,8R)-1-butanoyl-4-hydroxy-8-methyl-3,5,7-tris(3-methylbut-2-en-1-yl)-8-(4-methylpent-3-en-1-yl)bicyclo[3.3.1]non-3-ene-2,9-dione
• (1R,5R,7S,8R)-4-hydroxy-8-methyl-3,5,7-tris(3-methylbut-2-en-1-yl)-8-(4-methylpent-3-en-1-yl)-1-(2-methylpropanoyl)bicyclo[3.3.1]non-3-ene-2,9-dione
• (1R,5S,6R,7S)-4-Hydroxy-6-methyl-1,3,7-tris(3-methyl-2-buten-1-yl)-5-(2-methyl-1-oxopropyl)-6-(4-methyl-3-penten-1-yl)bicyclo[3.3.1]non-3-ene-2,9-dione
• 4-Hydroxy-6-methyl-1,3,7-tris(3-methyl-2-butenyl)-5-(2-methyl-1-oxopropyl)-6-(4-methyl-3-pentenyl) bicyclo(3.3.1)non-3-ene-2,9-dione
• Bicyclo(3.3.1)(1,4)benzodiazepin-5-one, 4-Hydroxy-6-methyl-1,3,7-tris(3-methyl-2-butenyl)-5-(2-methyl-1-oxopropyl)-6-(4-methyl-3-pentenyl)-, (1R,5S,6R,7S)-
• Bicyclo[3.3.1]non-3-ene-2,9-dione, 4-hydroxy-6-methyl-1,3,7-tris(3-methyl-2-buten-1-yl)-5-(2-methyl-1-oxopropyl)-6-(4-methyl-3-penten-1-yl)-, (1R,5S,6R,7S)-
• Bicyclo[3.3.1]non-3-ene-2,9-dione, 4-hydroxy-6-methyl-1,3,7-tris(3-methyl-2-butenyl)-5-(2-methyl-1-oxopropyl)-6-(4-methyl-3-pentenyl)-, (1R,5S,6R,7S)-
• Bicyclo[3.3.1]non-3-ene-2,9-dione, 4-hydroxy-6-methyl-1,3,7-tris(3-methyl-2-butenyl)-5-(2-methyl-1-oxopropyl)-6-(4-methyl-3-pentenyl)-, [1R-(6-endo,7-exo)]-
• Bicyclo[3.3.1]non-3-ene-2,9-dione, 4-hydroxy-6-methyl-1,3,7-tris(3-methyl-2-butenyl)-S-(2-methyl-1-oxopropyl)-6-(4-methyl-3-pentenyl)-, [1R-(1α,5α,6β,7α)]-
• Hsdb 7646
• Hyperforin
• Hyperforin (solution in Ethanol)
• (1R,5S)-4-Hydroxy-6-methyl-1,3,7β-tris(3-methyl-2-butenyl)-5-(2-methyl-1-oxopropyl)-6α-(4-methyl-3-pentenyl)bicyclo[3.3.1]non-3-ene-2,9-dione
• Bicyclo[3.3.1]non-3-ene-2,9-dione, 4-hydroxy-6-
• HYPERFORIN MIX(P)
• HYPERFORIN USP/EP/BP
• methyl-1,3,7-tris(3-methyl-2-buten-1-yl)-5-(2-methyl-1-oxopropyl)-6-(4-methyl-3-penten-1-yl)-,(1R,5S,6R,7S)-

Hyperforin

CAS: 11079-53-1

Hyperforin

Purity: ≥95%

Molecular weight: 536.79g/mol

Ref: 54-BUP22066

Hyperforin

CAS: 11079-53-1

Formula: C₃₅H₅₂O₄

Molecular weight: 536.78

Ref: 7W-GK2499

Hyperforin

CAS: 11079-53-1

Hyperforin, a natural product from Hypericum, is antidepress, inflammatory, antitumor and antiangiogenic effects, acts as a MRI and activates TRPC6 channels.

Formula: C₃₅H₅₂O₄

Purity: 98%

Color and Shape: White To Off-White Powder

Molecular weight: 536.79

Ref: TM-TN1755

Hyperforin

CAS: 11079-53-1

Formula: C₃₅H₅₂O₄

Purity: 95%~99%

Molecular weight: 536.797

Ref: BP-BP0751

Hyperforin

CAS: 11079-53-1

Formula: C₃₅H₅₂O₄

Molecular weight: 536.80

Ref: 4Z-H-101001

Hyperforin - solution in methanol

CAS: 11079-53-1

Lipophilic component of medicinal plant Hypericum perforatum (St John's wort) with anti-depressant activity. Uptake inhibitor of 5-HT, norephinephrine, dopamine, glutamate and GABA neurotransmitters. Also found to have anxiolytic, anti-proliferative and apoptosis-inducing properties.

Formula: C₃₅H₅₂O₄

Purity: Min. 80 Area-%

Color and Shape: Colorless Clear Liquid

Molecular weight: 536.78 g/mol

Ref: 3D-FH64889