CAS 11081-40-6

Sephadex G 15

Description:

Sephadex G-15 is a cross-linked dextran gel used primarily in biochemical applications, particularly for size exclusion chromatography. It is characterized by its porous structure, which allows for the separation of molecules based on their size. Sephadex G-15 has a specific pore size that is suitable for the fractionation of small biomolecules, such as peptides and nucleotides, typically in the molecular weight range of approximately 1,000 to 5,000 daltons. The gel is hydrophilic, which enhances its compatibility with aqueous solutions, making it ideal for use in biological and biochemical experiments. Sephadex G-15 is also chemically stable and inert, minimizing interactions with the substances being separated. Its ability to retain water while allowing smaller molecules to pass through makes it a valuable tool in purification processes. Additionally, it is often used in applications such as desalting and buffer exchange, where the removal of small contaminants from larger biomolecules is required. Overall, Sephadex G-15 is a versatile and widely used material in laboratory settings.

Formula: Unspecified

Synonyms:

• Sephadex G 15

Sephadex G-15

CAS: 11081-40-6

Sephadex G-15 is a type of ion-exchange resin that consists of a porous matrix with crosslinked polystyrene beads. It has been used in molecular biology and biochemistry for separation of biomolecules. Sephadex G-15 is capable of separating molecules based on hydrophobic interactions, size exclusion, or charge. The bead size can be varied to allow for separation of macromolecules such as proteins and nucleic acids. This medium has been used to purify erythrocyte enzyme systems and mitochondrial membranes. A 3-O-caffeoylquinic acid is found in the leaves of plants from the family Rubiaceae, as well as in the bark and root bark of some species from the genus Cinchona. These plants are known to have antihypertensive activity. Sephadex G-15 may also be used to separate antimicrobial peptides from spermatozoa and to isolate diabetics'

Purity: Min. 95%

Color and Shape: Powder

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