CAS 110871-86-8

Sparfloxacin

Description:

Sparfloxacin is a synthetic antibiotic belonging to the fluoroquinolone class, primarily used to treat bacterial infections. Its chemical structure features a bicyclic core with a fluorine atom, which enhances its antibacterial activity. Sparfloxacin exhibits broad-spectrum activity against both Gram-positive and Gram-negative bacteria, making it effective for respiratory tract infections, skin infections, and certain types of urinary tract infections. The mechanism of action involves the inhibition of bacterial DNA gyrase and topoisomerase IV, enzymes crucial for DNA replication and repair. Sparfloxacin is known for its favorable pharmacokinetic properties, including good oral bioavailability and a relatively long half-life, allowing for once-daily dosing. However, like other fluoroquinolones, it may be associated with side effects such as gastrointestinal disturbances, central nervous system effects, and potential tendon damage. Due to concerns about antibiotic resistance and adverse effects, its use is often reserved for specific indications where other antibiotics may not be effective. As with any antibiotic, appropriate use is critical to minimize resistance development.

Formula: C₁₉H₂₂F₂N₄O₃

InChI: InChI=1/C19H22FN3O3/c1-10-7-22(8-11(2)21-10)17-6-16-13(5-15(17)20)18(24)14(19(25)26)9-23(16)12-3-4-12/h5-6,9-12,21H,3-4,7-8H2,1-2H3,(H,25,26)

InChI key: InChIKey=DZZWHBIBMUVIIW-DTORHVGONA-N

SMILES: FC1=C2C(C(=O)C(C(O)=O)=CN2C3CC3)=C(N)C(F)=C1N4C[C@H](C)N[C@H](C)C4

Synonyms:

• 3-Quinolinecarboxylic acid, 5-amino-1-cyclopropyl-7-(3,5-dimethyl-1-piperazinyl)-6,8-difluoro-1,4-dihydro-4-oxo-, cis-
• rel-5-Amino-1-cyclopropyl-7-[(3R,5S)-3,5-dimethyl-1-piperazinyl]-6,8-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid
• AT 4140
• 3-Quinolinecarboxylic acid, 5-amino-1-cyclopropyl-7-[(3R,5S)-3,5-dimethyl-1-piperazinyl]-6,8-difluoro-1,4-dihydro-4-oxo-, rel-
• Sparfloxacin
• at4140
• 5-amino-1-cyclohexyl-7-(cis-3,5-dimethylpiperazino)-6,8-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid
• 5-amino-1-cyclopropyl-7-(3,5-dimethylpiperazin-1-yl)-6,8-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
• ,5-dimethyl-1-piperazinyl)-4-oxo-,cis-
• 1-cyclopropyl-7-(3,5-dimethylpiperazin-1-yl)-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
• SPARFLOXACIN, [2-14C]- 5-25 MCI(185-925 MBQ)/MMOL, DELIVERED >
• 5-amino-1-cyclopropyl-7-[(3R,5S)-3,5-dimethylpiperazin-1-yl]-6,8-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
• ci978
• Clorsulon, Vetranal
• 5-AMINO-1-CYCLOPROPYL-7-((3S,5R)-3,5-DIMETHYLPIPERAZIN-1-YL)-6,8-DIFLUORO-4-OXO-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID
• Spara
• Zagam
• CP 103826
• PD 1315-1
• SPARFLOXACIN, [2-14C]-5-25 MCI(185-925 MBQ)/MMOL, DELIVERED &gt
• 5-Amino-1-cyclopropyl-6,8-difluoro-1,4-dihydro-7-(3α,5α-dimethyl-1-piperazinyl)-4-oxoquinoline-3-carboxylic acid
• 3-Quinolinecarboxylic acid, 5-amino-1-cyclopropyl-7-[(3R,5S)-3,5-dimethyl-1-piperazinyl]-6,8-difluoro-1,4-dihydro-4-oxo-, rel-(9CI)
• PD-131501：Spara
• Sparfloxacin (base and/or unspecified salts)
• (cis)-5-Amino-1-cyclopropyl-6，8-difluoro-1，4-dihydro-7-(3，5-dimethyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid

Sparfloxacin, 98%

CAS: 110871-86-8

Sparfloxacin, 98%

Formula: C₁₉H₂₂F₂N₄O₃

Purity: 98%

Molecular weight: 392.41

Ref: 02-J66358

Sparfloxacin

CAS: 110871-86-8

Sparfloxacin (CI-978) is a fluoroquinolone antibiotic that inhibits bacterial DNA gyrase, thereby inhibiting DNA replication and transcription.

Formula: C₁₉H₂₂F₂N₄O₃

Purity: 99.67% - >99.99%

Color and Shape: Light Yellow Powder

Molecular weight: 392.40

Ref: TM-T1095

Sparfloxacin

CAS: 110871-86-8

Formula: C₁₉H₂₂F₂N₄O₃

Purity: %

Color and Shape: Solid

Molecular weight: 392.3998

Ref: IN-DA007U3N

Sparfloxacin

CAS: 110871-86-8

Sparfloxacin

Formula: C₁₉H₂₂F₂N₄O₃

Purity: 98.8% (Typical Value in Batch COA)

Color and Shape: yellow crystalline powder

Molecular weight: 392.40g/mol

Ref: 54-BIB1480

Sparfloxacin

CAS: 110871-86-8

Formula: C₁₉H₂₂F₂N₄O₃

Color and Shape: Yellow Solid

Molecular weight: 392.41

Ref: 4Z-S-071

Sparfloxacin

CAS: 110871-86-8

Sparfloxacin

Purity: ≥98%

Molecular weight: 392.4g/mol

Ref: 54-BUP16112

Sparfloxacin

CAS: 110871-86-8

Formula: C₁₉H₂₂F₂N₄O₃

Purity: ≥ 98.0% (dried basis)

Color and Shape: White to light-yellow powder

Molecular weight: 392.4

Ref: 7W-GA1910

Sparfloxacin

CAS: 110871-86-8

Formula: C₁₉H₂₂F₂N₄O₃

Color and Shape: Neat

Molecular weight: 392.40

Ref: 04-C16972650

Sparfloxacin-d4

CAS: 110871-86-8

Formula: C₁₉H₁₈D₄F₂N₄O₃

Molecular weight: 396.43

Ref: 4Z-S-078

Sparfloxacin

CAS: 110871-86-8

Formula: C₁₉H₂₂F₂N₄O₃

Color and Shape: Light Yellow To Yellow

Molecular weight: 392.40

Ref: TR-S679250

Sparfloxacin

CAS: 110871-86-8

Fluoroquinolone; inhibits bacterial DNA gyrase

Formula: C₁₉H₂₂F₂N₄O₃

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 392.4 g/mol

Ref: 3D-AS27858

Sparfloxacin

CAS: 110871-86-8

Purity: 99+%

Molecular weight: 392.41

Ref: 10-F241970

Sparfloxacin-d4

Controlled Product

CAS: 110871-86-8

Formula: C₁₉D₄H₁₈F₂N₄O₃

Color and Shape: Neat

Molecular weight: 396.424

Ref: TR-S679252