CAS 11088-09-8

Wilforine

Description:

Wilforine, with the CAS number 11088-09-8, is a chemical compound that belongs to the class of alkaloids. It is primarily derived from the plant species Wilfordia ebracteata, which is known for its medicinal properties. The compound exhibits a range of biological activities, including potential anti-inflammatory and analgesic effects, making it of interest in pharmacological research. Wilforine is characterized by its complex molecular structure, which contributes to its biological activity. It is typically studied for its interactions with various biological targets, including enzymes and receptors. The compound's solubility, stability, and reactivity can vary depending on environmental conditions, such as pH and temperature. As with many alkaloids, safety and toxicity profiles are crucial for its application in medicinal chemistry. Ongoing research aims to further elucidate its mechanisms of action and potential therapeutic uses, particularly in traditional medicine contexts.

Formula: C₄₃H₄₉NO₁₈

InChI: InChI=1S/C43H49NO18/c1-21-16-17-29-28(15-12-18-44-29)39(52)55-19-40(7)30-31(56-23(3)46)35(58-25(5)48)42(20-54-22(2)45)36(59-26(6)49)32(60-38(51)27-13-10-9-11-14-27)34(61-37(21)50)41(8,53)43(42,62-40)33(30)57-24(4)47/h9-15,18,21,30-36,53H,16-17,19-20H2,1-8H3/t21-,30+,31+,32-,33+,34-,35+,36-,40-,41-,42+,43-/m0/s1

InChI key: InChIKey=ZOCKGJZEUVPPPI-QSNSFFMXSA-N

SMILES: C(OC(C)=O)[C@]12[C@@]34[C@H](OC(C)=O)[C@]([C@@](C)(O3)COC(=O)C=5C(CC[C@H](C)C(=O)O[C@]([C@]4(C)O)([C@H](OC(=O)C6=CC=CC=C6)[C@@H]1OC(C)=O)[H])=NC=CC5)([C@@H](OC(C)=O)[C@H]2OC(C)=O)[H]

Synonyms:

• Evonimine, 8-(acetyloxy)-O2-benzoyl-O2-deacetyl-8-deoxo-, (8α)-
• 8,11-Epoxy-9,12-ethano-11,15-methano-5H,11H-[1,9]dioxacyclooctadecino[4,3-b]pyridine-5,17(18H)-dione, 10,13,22,23-tetrakis(acetyloxy)-12-[(acetyloxy)methyl]-14-(benzoyloxy)-7,8,9,10,12,13,14,15,19,20-decahydro-21-hydroxy-8,18,21-trimethyl-, (8R,9R,10R,11S,12S,13R,14R,15S,18S,21S,22S,23R)-
• (8R,9R,10R,11S,12S,13R,14R,15S,18S,21S,22S,23R)-10,13,22,23-Tetrakis(acetyloxy)-12-[(acetyloxy)methyl]-14-(benzoyloxy)-7,8,9,10,12,13,14,15,19,20-decahydro-21-hydroxy-8,18,21-trimethyl-8,11-epoxy-9,12-ethano-11,15-methano-5H,11H-[1,9]dioxacyclooctadecino[4,3-b]pyridine-5,17(18H)-dione
• Wilforine
• 8,11-Epoxy-9,12-ethano-11,15-methano-5H,11H-[1,9]dioxacyclooctadecino[4,3-b]pyridine-5,17(18H)-dione, 10,13,22,23-tetrakis(acetyloxy)-12-[(acetyloxy)methyl]-14-(benzoyloxy)-7,8,9,10,12,13,14,15,19,20-decahydro-21-hydroxy-8,18,21-trimethyl-, [8R-(8R*,9R*,10R*,11S*,12S*,13R*,14R*,15S*,18S*,21S*,22S*,23R*)]-

(8R,9R,10R,11S,12S,13R,14R,15S,18S,21S,22S,23R)-10,13,22,23-Tetrakis(acetyloxy)-12-[(acetyloxy)methyl]-14-(benzoyloxy)-7,8,9,10,12,13,14,15,19,20-decahydro-21-hydroxy-8,18,21-trimethyl-8,11-epoxy-9,12-ethano-11,15-methano-5H,11H-[1,9]dioxacyclooctadecino[4,3-b]pyridine-5,17(18H)-dione

CAS: 11088-09-8

Formula: C₄₃H₄₉NO₁₈

Purity: %

Molecular weight: 867.8451

Ref: IN-DA008TNF

Wilforine

CAS: 11088-09-8

Wilforine

Purity: ≥98%

Molecular weight: 867.85g/mol

Ref: 54-BUP03408

Wilforine

CAS: 11088-09-8

Formula: C₄₃H₄₉NO₁₈

Molecular weight: 867.85

Ref: 7W-GY2293

Wilforine

CAS: 11088-09-8

Wilforine has anti-inflammatory effect, which might be mediated by down-regulation of the expression of inflammatory factors TNF-α, IL-6 and NO. It also has insecticidal activity by inhibiting the Na+-K+-ATPase in the central nervous system.

Formula: C₄₃H₄₉NO₁₈

Purity: 95%~99%

Color and Shape: Powder

Molecular weight: 867.854

Ref: BP-BP1588

Wilforine

CAS: 11088-09-8

Wilforine: a sesquiterpene alkaloid from T. wilfordii, treats pulmonary fibrosis, has anti-inflammatory and insecticidal properties.

Formula: C₄₃H₄₉NO₁₈

Purity: 98.67% - 99.85%

Color and Shape: Solid

Molecular weight: 867.85

Ref: TM-T6S1049

Wilforine

CAS: 11088-09-8

Natural alkaloid

Formula: C₄₃H₄₉NO₁₈

Purity: ≥ 95.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 867.86

Ref: 5G-83298

Wilforine

CAS: 11088-09-8

Wilforine is a natural diterpenoid alkaloid derived from the root of the *Tripterygium wilfordii* plant, a species widely explored for its bioactive compounds. As a member of the alkaloid family, Wilforine exhibits a complex chemical structure that underlies its biological activities. The mode of action of Wilforine is multifaceted, involving the modulation of immune system components and inhibition of various signaling pathways. This contributes to its anti-inflammatory and immunosuppressive properties.

Formula: C₄₃H₄₉NO₁₈

Purity: Min. 96 Area-%

Color and Shape: White Powder

Molecular weight: 867.85 g/mol

Ref: 3D-FW74254