(N-Me-Phe7)-Neurokinin B is a synthetic analog of neurokinin B, a neuropeptide that plays a crucial role in various physiological processes, including pain perception, inflammation, and the regulation of reproductive functions. This compound is characterized by the presence of a modified phenylalanine residue, where the nitrogen atom is methylated, enhancing its stability and receptor affinity. It primarily interacts with neurokinin receptors, particularly the NK3 receptor, which is involved in mediating the effects of neurokinin B in the central nervous system. The modification of the phenylalanine residue contributes to its pharmacological properties, making it a valuable tool in research related to neurokinin signaling pathways. Additionally, (N-Me-Phe7)-Neurokinin B is often studied for its potential therapeutic applications in conditions such as anxiety, depression, and reproductive disorders. Its structural characteristics, including peptide bonds and specific amino acid substitutions, influence its biological activity and receptor selectivity, making it a significant compound in neuropharmacology.

(N-Me-Phe7)-Neurokinin B

110880-53-0: (N-Me-Phe7)-Neurokinin B is a synthetic analog of neurokinin B, a neuropeptide that plays a crucial role in various physiological processes, including pain perception, inflammation, and the regulation of reproductive functions. This compound is characterized by the presence of a modified phenylalanine residue, where the nitrogen atom is methylated, enhancing its stability and receptor affinity. It primarily interacts with neurokinin receptors, particularly the NK3 receptor, which is involved in mediating the effects of neurokinin B in the central nervous system. The modification of the phenylalanine residue contributes to its pharmacological properties, making it a valuable tool in research related to neurokinin signaling pathways. Additionally, (N-Me-Phe7)-Neurokinin B is often studied for its potential therapeutic applications in conditions such as anxiety, depression, and reproductive disorders. Its structural characteristics, including peptide bonds and specific amino acid substitutions, influence its biological activity and receptor selectivity, making it a significant compound in neuropharmacology.

The MePhe-analog of NKB shows high selectivity for NKB receptors.

(N-Me-Phe⁷)-Neurokinin B

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CAS 110880-53-0

(N-Me-Phe7)-Neurokinin B

(N-Me-Phe⁷)-Neurokinin B

Ref: 01-4016322

(N-Me-Phe7)-Neurokinin B trifluoroacetate salt

Ref: 3D-FM110410