CAS 110882-81-0

parvodicin A

Description:

Parvodicin A is a natural product classified as a polyketide, specifically belonging to the family of compounds known as anthracyclines. It is derived from the fermentation of certain Streptomyces species. Parvodicin A exhibits notable biological activity, particularly as an antitumor agent, and has been studied for its potential therapeutic applications in cancer treatment. The compound is characterized by its complex molecular structure, which includes multiple rings and functional groups that contribute to its biological efficacy. Its mechanism of action typically involves intercalation into DNA, leading to disruption of replication and transcription processes in rapidly dividing cancer cells. Additionally, parvodicin A may exhibit cytotoxic effects and influence various cellular pathways, making it a subject of interest in medicinal chemistry and drug development. As with many natural products, the study of parvodicin A also emphasizes the importance of understanding its pharmacokinetics, toxicity, and potential side effects in clinical applications.

Formula: C₈₁H₈₄Cl₂N₈O₂₉

InChI: InChI=1/C81H84Cl2N8O29/c1-3-4-5-6-7-8-9-10-54(97)86-77-68(102)66(100)56(78(110)111)80(120-77)119-70-51-25-36-26-52(70)116-48-20-15-35(23-43(48)82)64(98)63-76(109)90-62(79(112)113)41-27-37(93)28-50(117-81-69(103)67(101)65(99)53(31-92)118-81)55(41)40-22-33(13-18-45(40)94)59(73(106)91-63)87-74(107)60(36)88-75(108)61-42-29-39(30-47(96)57(42)83)115-49-24-34(14-19-46(49)95)58(84-2)72(105)85-44(71(104)89-61)21-32-11-16-38(114-51)17-12-32/h11-20,22-30,44,53,56,58-69,77,80-81,84,92-96,98-103H,3-10,21,31H2,1-2H3,(H,85,105)(H,86,97)(H,87,107)(H,88,108)(H,89,104)(H,90,109)(H,91,106)(H,110,111)(H,112,113)

Synonyms:

• Parvodicin C1
• Ristomycin A aglycone, 5,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-56-O-[2-deoxy-2-[(1-oxodecyl)amino]-β-D-glucopyranuronosyl]-42-O-α-D-mannopyranosyl-N15-methyl- (9CI)
• Parvodicin A
• Parvodicin B2
• parvodicin A
• Parvodicin C2
• Ristomycin A aglycone, 5,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-56-O-(2-deoxy-2-((1-oxodecyl)amino)-beta-D-glucopyranuronosyl)-42-O-alpha-D-mannopyranosyl-N15-methyl-
• Parvodicin C3
• Parvodicin B1
• Parvodicin C4

Parvodicin A

CAS: 110882-81-0

Parvodicin A is a glycopeptide antibiotic that exhibits inhibitory effects against Staphylococcus aureus, Staphylococcus epidermidis, Staphylococcus haemolyticus, and Enterococcus faecalis.

Formula: C₈₁H₈₄Cl₂N₈O₂₉

Color and Shape: Solid

Molecular weight: 1704.48

Ref: TM-TN10657