CAS 110882-84-3
:Ristomycin A aglycone,5,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-56-O-[2-deoxy-2-[(10-methyl-1-oxoundecyl)amino]-b-D-glucopyranuronosyl]-42-O-a-D-mannopyranosyl-N15-methyl-
Description:
Ristomycin A aglycone is a complex glycosylated antibiotic compound derived from the actinobacterium Amycolatopsis orientalis. It is characterized by its intricate structure, which includes multiple chlorinated and demethylated functional groups, contributing to its biological activity. The presence of various sugar moieties, such as 2-deoxy-2-[(10-methyl-1-oxoundecyl)amino]-β-D-glucopyranuronosyl and α-D-mannopyranosyl, enhances its solubility and interaction with biological targets. This compound exhibits potent antimicrobial properties, particularly against Gram-positive bacteria, making it valuable in the field of medicinal chemistry. Its mechanism of action typically involves interference with bacterial protein synthesis. The structural complexity, including multiple chiral centers and functional groups, presents challenges in synthesis and characterization, but also offers opportunities for the development of novel derivatives with improved efficacy or reduced toxicity. Overall, Ristomycin A aglycone represents a significant example of natural product chemistry with potential therapeutic applications.
Formula:C83H88Cl2N8O29
Synonyms:- Antibiotic A 40926B
- Parvodicin C1
- 1H,15H,34H-20,23:30,33-Dietheno-3,18:35,48-bis(iminomethano)-4,8:10,14:25,28:43,47-tetrametheno-28H-[1,14,6,22]dioxadiazacyclooctacosino[4,5-m][10,2,16]benzoxadiazacyclotetracosine,ristomycin A aglycone deriv.
- Antibiotic A 40926 factorB0
- B0-A 40926
- A40926 B0
- A 40926B
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