CAS 110925-92-3

ROXATIDINE OXALATE

Description:

Roxatidine oxalate is a pharmaceutical compound primarily used as an antihistamine and an H2 receptor antagonist, which helps reduce stomach acid production. It is often utilized in the treatment of conditions such as peptic ulcers and gastroesophageal reflux disease (GERD). The substance is characterized by its ability to selectively block histamine H2 receptors in the gastric parietal cells, leading to decreased secretion of gastric acid. Roxatidine oxalate is typically administered orally and is known for its relatively long duration of action compared to other H2 antagonists. In terms of its chemical structure, it features a pyridine ring and an oxalate moiety, contributing to its pharmacological properties. The compound is generally well-tolerated, but like all medications, it may have side effects, including gastrointestinal disturbances or central nervous system effects in some patients. Its safety profile and efficacy have made it a valuable option in managing acid-related disorders.

Formula: C₁₉H₂₈N₂O₇

Synonyms:

• Roxtidine oxalate
• N-[3-[3-(piperidinomethyl)phenoxy]-propyl]-hydroxyacetamide oxalate
• 2-Hydroxy-N-[3-[3-(1-piperidinylMethyl)phenoxy]propyl]acetaMide Ethanedioate
• Roxatidine（Halfoxalate）
• Roxatidine ethanedioate (2:1) (salt)
• Roxatidine acetate intermediate
• ROXATIDINE OXALATE
• 2-Hydroxy-N-[3-[3-(1-piperidinylmethyl)phenoxy]propyl]acetamide ethanedioate (2:1) (salt)
• Roxatidine HeMioxalate
• 2-hydro-N-[3-[3-(1-piperidinylMethyl)phenoxy]propyl]acetaMide ethanedioate (2︰1) (salt)

ROXATIDINE OXALATE

CAS: 110925-92-3

Formula: C₃₆H₅₄N₄O₁₀

Purity: 98%

Color and Shape: Solid

Molecular weight: 702.8348

Ref: IN-DA008R2N

Roxatidine Hemioxalate

CAS: 110925-92-3

Formula: C₁₇H₂₆N₂O₃·5C₂H₂O₄

Color and Shape: White To Off-White Solid

Molecular weight: 306.41 0.5*90.03

Ref: 4Z-R-401

Roxatidine Hemioxalate

Controlled Product

CAS: 110925-92-3

Applications The major metabolite of Roxatidine Acetate (R700870).
References Ward, D., et al.: J. Med. Chem., 25, 490 (1982), Tarutani, M., et al.: Arzneim.-Forsch., 35, 703 (1985),

Formula: C₁₇H₂₆N₂O₃·C₂H₂O₄

Color and Shape: Neat

Molecular weight: 396.43

Ref: TR-R700860

Roxatidine hemioxalate

CAS: 110925-92-3

Roxatidine hemioxalate is a sulfate salt of roxatidine, which is a synthetic, long-acting H2-receptor antagonist. It is used to treat peptic ulcers and gastroesophageal reflux disease (GERD). Roxatidine hemioxalate has a high yield in its synthesis and can be produced in a multistep process that includes the reaction of piperidine with benzyl alcohol. The product is purified by filtration and analyzed for chloride content.

Formula: C₁₉H₂₈N₂O₇

Purity: Min. 95%

Molecular weight: 396.4 g/mol

Ref: 3D-KEA92592