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CAS 110927-46-3

:

22-hydroxycholecalciferol

Description:
22-Hydroxycholecalciferol, also known as 22-hydroxyvitamin D3, is a derivative of vitamin D3 (cholecalciferol) that plays a significant role in calcium and phosphate metabolism in the body. This compound is characterized by the presence of a hydroxyl group at the 22nd carbon position, which differentiates it from other vitamin D metabolites. It is a fat-soluble vitamin, meaning it is soluble in lipids and can be stored in body fat. The substance is involved in various biological processes, including the regulation of gene expression and the modulation of immune function. Its synthesis occurs in the liver and kidneys, where it is converted into its active forms. 22-Hydroxycholecalciferol is often studied for its potential therapeutic effects, particularly in bone health and metabolic disorders. Due to its structural similarity to other vitamin D compounds, it may exhibit similar biological activities, although its specific effects and mechanisms of action are still under investigation. As with other vitamin D derivatives, it is important to consider its dosage and potential toxicity in clinical applications.
Formula:C27H44O2
InChI:InChI=1/C27H44O2/c1-18(2)8-15-26(29)20(4)24-13-14-25-21(7-6-16-27(24,25)5)10-11-22-17-23(28)12-9-19(22)3/h10-11,18,20,23-26,28-29H,3,6-9,12-17H2,1-2,4-5H3/b21-10+,22-11-/t20-,23+,24+,25-,26-,27+/m0/s1
Synonyms:
  • (3R,5Z,7E,22S)-9,10-secocholesta-5,7,10-triene-3,22-diol
  • 22-Hydroxyvitamin D3
  • 9,10-Secocholesta-5,7,10(19)-triene-3,22-diol, (3beta,5Z,7E,22S)-
  • 9,10-Secocholesta-5,7,10(19)-triene-3,22-diol, (3β,5Z,7E,22S)- (9CI)
  • 22-hydroxycholecalciferol
  • 22-Hydroxycholecalciferol
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