CAS 110952-70-0: cotinine-methyl-D3

Description: Cotinine-methyl-D3, with the CAS number 110952-70-0, is a deuterated derivative of cotinine, which is a metabolite of nicotine. This compound is characterized by the incorporation of deuterium, a stable isotope of hydrogen, at specific positions in the molecule, which enhances its utility in various analytical applications, particularly in pharmacokinetic studies and metabolic research. The presence of deuterium allows for improved detection and quantification in mass spectrometry due to its distinct mass signature. Cotinine itself is known for its role in tobacco research, as it serves as a biomarker for nicotine exposure. The deuterated form, cotinine-methyl-D3, is often used in studies to trace nicotine metabolism and to understand the pharmacological effects of tobacco products. Its chemical structure retains the core features of cotinine, including the pyridine ring and the carbonyl group, while the deuterium substitution can influence its physical and chemical properties, such as solubility and stability. Overall, cotinine-methyl-D3 is a valuable tool in the field of biochemistry and toxicology.

Formula: C₁₀H₉D₃N₂O

InChI: InChI=1/C10H12N2O/c1-12-9(4-5-10(12)13)8-3-2-6-11-7-8/h2-3,6-7,9H,4-5H2,1H3/i1D3

Synonyms:

• 1-(2H3)methyl-5-pyridin-3-ylpyrrolidin-2-one

Cotinine-d3

CAS: 110952-70-0

• Formula: C₁₀H₉N₂OD₃
• Molecular weight: 179.24

(+/-)-Cotinine-d3(N-methyl-d3)

CAS: 110952-70-0

• Purity: 99 atom % D
• Color and Shape: White-Pale Yellow Solid
• Molecular weight: 179.24

rac-Cotinine-d3

CAS: 110952-70-0

Stability Hygroscopic Applications A labelled major metabolite of nicotine in humans. Carcinogen. References Sugasawa, S., …

• Formula: C₁₀H₃H₉N₂O
• Color and Shape: Off-White To Brown
• Molecular weight: 179.23

rac-Cotinine-d3 (0.1 mg/mL in Methanol)

CAS: 110952-70-0

• Formula: C₁₀H₃H₉N₂O
• Color and Shape: Colourless
• Molecular weight: 179.23

rac-Cotinine-d3 (1.0 mg/mL in Methanol)

CAS: 110952-70-0

• Formula: C₁₀H₃H₉N₂O
• Color and Shape: Colourless
• Molecular weight: 179.23

(±)-Cotinine-d3 solution, 1.0 mg/mL in methanol, ampule of 1 mL

CAS: 110952-70-0

Cotinine is a major metabolite of nicotine that can be used as an indicator of …

• Formula: C₁₀H₉D₃N₂O
• Purity: Min. 95%
• Color and Shape: Clear Liquid
• Molecular weight: 179.23 g/mol