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CAS 110990-08-4

:

Fmoc-D-Lysine

Description:
Fmoc-D-Lysine, with the CAS number 110990-08-4, is a derivative of the amino acid lysine, specifically modified with a fluorenylmethyloxycarbonyl (Fmoc) protecting group. This compound is characterized by its ability to protect the amino group of lysine during peptide synthesis, allowing for selective reactions at other functional groups. Fmoc-D-Lysine is typically used in solid-phase peptide synthesis, where the Fmoc group can be easily removed under basic conditions, facilitating the sequential addition of amino acids. The presence of the D-configuration of lysine distinguishes it from its L-counterpart, influencing the stereochemistry and biological activity of the resulting peptides. Fmoc-D-Lysine is soluble in organic solvents such as dimethylformamide (DMF) and dimethyl sulfoxide (DMSO), and it is generally stable under standard laboratory conditions. Its applications extend to the fields of biochemistry and medicinal chemistry, particularly in the design and synthesis of peptide-based therapeutics and research tools.
Formula:C21H24N2O4
InChI:InChI=1/C21H24N2O4.ClH/c22-12-6-5-11-19(20(24)25)23-21(26)27-13-18-16-9-3-1-7-14(16)15-8-2-4-10-17(15)18;/h1-4,7-10,18-19H,5-6,11-13,22H2,(H,23,26)(H,24,25);1H/t19-;/m1./s1
InChI key:InChIKey=YRKFMPDOFHQWPI-LJQANCHMSA-N
SMILES:C(OC(N[C@H](CCCCN)C(O)=O)=O)C1C=2C(C=3C1=CC=CC3)=CC=CC2
Synonyms:
  • (2R)-6-Amino-2-([[(9H-fluoren-9-yl)methoxy]carbonyl]amino)hexanoic acid
  • (R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-6-aminohexanoic acid
  • <span class="text-smallcaps">D</span>-Lysine, N<sup>2</sup>-[(9H-fluoren-9-ylmethoxy)carbonyl]-
  • D-Lys(Fmoc)
  • D-lysine, N~2~-[(9H-fluoren-9-ylmethoxy)carbonyl]-
  • Fmoc-<span class="text-smallcaps">D</span>-Lysine
  • Fmoc-D-Lys-OH
  • N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-lysine hydrochloride (1:1)
  • N<sup>2</sup>-[(9H-Fluoren-9-ylmethoxy)carbonyl]-<span class="text-smallcaps">D</span>-lysine
  • N~2~-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-lysine
  • See more synonyms
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