CAS 111025-46-8
:Pioglitazone
Description:
Pioglitazone is an antidiabetic medication primarily used to manage type 2 diabetes mellitus. It belongs to the thiazolidinedione class of drugs, which function as agonists of the peroxisome proliferator-activated receptor gamma (PPAR-γ). This mechanism enhances insulin sensitivity in muscle and adipose tissue, thereby improving glucose uptake and utilization. Pioglitazone is typically administered orally and is often prescribed in conjunction with other antidiabetic agents. The substance is characterized by its chemical formula, which includes carbon, hydrogen, nitrogen, and oxygen atoms, and it exhibits a relatively high lipophilicity, influencing its absorption and distribution in the body. Common side effects may include weight gain, edema, and an increased risk of heart failure, necessitating careful patient monitoring. Additionally, pioglitazone has been associated with potential risks of bladder cancer, leading to specific recommendations regarding its use. Overall, pioglitazone plays a significant role in diabetes management, particularly for patients who are insulin-resistant.
Formula:C19H21ClN2O3S
InChI:InChI=1/C19H20N2O3S.ClH/c1-2-13-3-6-15(20-12-13)9-10-24-16-7-4-14(5-8-16)11-17-18(22)21-19(23)25-17;/h3-8,12,17H,2,9-11H2,1H3,(H,21,22,23);1H
InChI key:InChIKey=HYAFETHFCAUJAY-UHFFFAOYSA-N
SMILES:C(C1C(=O)NC(=O)S1)C2=CC=C(OCCC3=CC=C(CC)C=N3)C=C2
Synonyms:- 5-{4-[2-(5-ethylpyridin-2-yl)ethoxy]benzyl}-1,3-thiazolidine-2,4-dione
- Pioglitazone base
- PINEPOLLEN
- KY-18
- 5-[[4-[2-(5-ethylpyridin-2-yl)ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione
- 5-(4-[2-(5-ETHYL-PYRIDIN-2-YL)-ETHOXY]-BENZYL)-THIAZOLIDINE-2,4-DIONE
- 5-[4-[2-(5-ETHYL-2-PYRIDINYL)ETHOXY]PHENYL]METHYL-2,4-THIAZOLIDINEDIONE
- Pioglitazone and its intermeidates
- Pioglitazone free base
- PIOGLITAZONE HCL(5-[[4-[2-(5-ETHYLPYRIDIN-2-YL)ETHOXY]PHENYL]METHYL]THIAZOLIDINE-2,4-DIONE, HCL)
- 5-{4-[2-(5-ethylpyridin-2-yl)ethoxy]benzyl}-1,3-thiazolidine-2,4-dione hydrochloride (1:1)
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 11 products.
Pioglitazone Hydrochloride
CAS:Formula:C19H20N2O3S·HClPurity:>98.0%(HPLC)(N)Color and Shape:White to Almost white powder to crystalMolecular weight:392.905-({4-[2-(5-ethylpyridin-2-yl)ethoxy]phenyl}methyl)-1,3-thiazolidine-2,4-dione
CAS:Formula:C19H20N2O3SPurity:98%Color and Shape:SolidMolecular weight:356.4387Pioglitazone
CAS:Pioglitazone (U 72107) is a selective and oral PPARγ agonist with EC50 of 0.93 and 0.99 μM on human and mouse PPARγ, respectively . High-Quality, Low-Cost!Formula:C19H20N2O3SPurity:95% - 99.57%Color and Shape:White PowderMolecular weight:356.44Pioglitazone
CAS:Formula:C19H20N2O3SPurity:≥ 98%Color and Shape:White to off-white powder or solidMolecular weight:356.445-(4-(2-(5-Ethylpyridin-2-Yl)Ethoxy)Benzyl)Thiazolidine-2,4-Dione
CAS:5-(4-(2-(5-Ethylpyridin-2-Yl)Ethoxy)Benzyl)Thiazolidine-2,4-DionePurity:99%Molecular weight:356.44g/molPioglitazone-d4 Hydrochloride
CAS:Controlled Product<p>Applications Pioglitazone-d4 is the labeled analogue of Pioglitazone (P469995), which shows antidiabetic activity in patients with type 2 diabetes mellitus.<br>References DeFronzo, R.A., et. al.: Diabetes, 62, 3920 (2013)<br></p>Formula:C19H17D4ClN2O3SColor and Shape:NeatMolecular weight:396.92Pioglitazone
CAS:Controlled Product<p>Applications Pioglitazone shows antidiabetic activity in patients with type 2 diabetes mellitus.<br>References DeFronzo, R.A., et. al.: Diabetes, 62, 3920 (2013)<br></p>Formula:C19H20N2O3SColor and Shape:NeatMolecular weight:356.44Pioglitazone - Bio-X ™
CAS:<p>Pioglitazone is a thiazolidinedione drug that is used in combination with diet change and exercise to treat glycemic levels in patients with type 2 diabetes mellitus. This drug is an agonist of peroxisome proliferator-activated receptor-gamma and increases glucose uptake. In animal studies, Pioglitazone has shown to have anti-inflammatory properties.</p>Formula:C19H20N2O3SPurity:Min. 95%Color and Shape:PowderMolecular weight:356.44 g/molPioglitazone base
CAS:<p>Agonist of peroxisome proliferator-activated receptor-γ (PPARγ), useful for the treatment and prevention of type 2 diabetes mellitus. It belongs to the class of thiazolidinediones (TZDs), which increase insulin sensitivity and glucose uptake in peripheral tissues. It reduces the risk of cardiovascular disease and was shown to atheroprotective and anti-inflammatory effects in animal models.</p>Formula:C19H20N2O3SPurity:Min. 95%Color and Shape:White PowderMolecular weight:356.44 g/mol
![5-({4-[2-(5-ethylpyridin-2-yl)ethoxy]phenyl}methyl)-1,3-thiazolidine-2,4-dione](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA00HBSN.jpg&w=3840&q=75)
