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Pioglitazone

CAS 111025-46-8: Pioglitazone

Description:Pioglitazone is an antidiabetic medication primarily used to manage type 2 diabetes mellitus. It belongs to the thiazolidinedione class of drugs, which function as agonists of the peroxisome proliferator-activated receptor gamma (PPAR-γ). This mechanism enhances insulin sensitivity in muscle and adipose tissue, thereby improving glucose uptake and utilization. Pioglitazone is typically administered orally and is often prescribed in conjunction with other antidiabetic agents. The substance is characterized by its chemical formula, which includes carbon, hydrogen, nitrogen, and oxygen atoms, and it exhibits a relatively high lipophilicity, influencing its absorption and distribution in the body. Common side effects may include weight gain, edema, and an increased risk of heart failure, necessitating careful patient monitoring. Additionally, pioglitazone has been associated with potential risks of bladder cancer, leading to specific recommendations regarding its use. Overall, pioglitazone plays a significant role in diabetes management, particularly for patients who are insulin-resistant.

Formula:C19H21ClN2O3S

InChI:InChI=1/C19H20N2O3S.ClH/c1-2-13-3-6-15(20-12-13)9-10-24-16-7-4-14(5-8-16)11-17-18(22)21-19(23)25-17;/h3-8,12,17H,2,9-11H2,1H3,(H,21,22,23);1H

InChI key:InChIKey=HYAFETHFCAUJAY-UHFFFAOYSA-N

SMILES:O=C1SC(C(=O)N1)CC2=CC=C(OCCC3=NC=C(C=C3)CC)C=C2

  • Synonyms:
  • 5-{4-[2-(5-ethylpyridin-2-yl)ethoxy]benzyl}-1,3-thiazolidine-2,4-dione
  • Pioglitazone base
  • PINEPOLLEN
  • KY-18
  • 5-[[4-[2-(5-ethylpyridin-2-yl)ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione
  • 5-(4-[2-(5-ETHYL-PYRIDIN-2-YL)-ETHOXY]-BENZYL)-THIAZOLIDINE-2,4-DIONE
  • 5-[4-[2-(5-ETHYL-2-PYRIDINYL)ETHOXY]PHENYL]METHYL-2,4-THIAZOLIDINEDIONE
  • Pioglitazone and its intermeidates
  • Pioglitazone free base
  • PIOGLITAZONE HCL(5-[[4-[2-(5-ETHYLPYRIDIN-2-YL)ETHOXY]PHENYL]METHYL]THIAZOLIDINE-2,4-DIONE, HCL)
  • See more synonyms
  • 5-{4-[2-(5-ethylpyridin-2-yl)ethoxy]benzyl}-1,3-thiazolidine-2,4-dione hydrochloride (1:1)
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Found 10 products.

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Pioglitazone Hydrochloride

CAS:111025-46-8112529-15-4

Ref: 3B-P1901

5g83.00 €
25g288.00 €
Estimated delivery in United States, on Thursday 27 Feb 2025
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Pioglitazone

CAS:111025-46-8

Ref: TM-T0214

5mg42.00 €
10mg52.00 €
25mg69.00 €
50mg97.00 €
100mg140.00 €
500mg334.00 €
1mL*10mM (DMSO)55.00 €
Estimated delivery in United States, on Thursday 6 Mar 2025
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Ref: IN-DA00HBSN

1g131.00 €
5g477.00 €
25gTo inquire
10mg37.00 €
50mg50.00 €
250mg62.00 €
Estimated delivery in United States, on Thursday 6 Mar 2025
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Pioglitazone

CAS:111025-46-8

Ref: 7W-GP2624

1mg79.00 €
5mg101.00 €
25mg179.00 €
Estimated delivery in United States, on Friday 7 Mar 2025
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5-(4-(2-(5-Ethylpyridin-2-Yl)Ethoxy)Benzyl)Thiazolidine-2,4-Dione

CAS:111025-46-8

Ref: 54-OR1011705

1g103.00 €
5g365.00 €
25g1,178.00 €
250mg45.00 €
Estimated delivery in United States, on Friday 7 Mar 2025
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Pioglitazone-d4 Hydrochloride

Controlled Product
CAS:111025-46-81134163-29-3

Ref: TR-P469997

1mg340.00 €
10mg2,186.00 €
Estimated delivery in United States, on Tuesday 18 Mar 2025
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PIOGLITAZONE

CAS:111025-46-8

Ref: 10-F386732

1g94.00 €
5gTo inquire
10gTo inquire
Estimated delivery in United States, on Tuesday 18 Mar 2025
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Pioglitazone

Controlled Product
CAS:111025-46-8

Ref: TR-P469995

1g343.00 €
25mg153.00 €
100mg251.00 €
Estimated delivery in United States, on Tuesday 18 Mar 2025
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Pioglitazone - Bio-X ™

CAS:111025-46-8

Ref: 3D-BP164273

50mg149.00 €
Estimated delivery in United States, on Monday 17 Mar 2025
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Pioglitazone base

CAS:111025-46-8

Ref: 3D-FP39372

2g318.00 €
5g586.00 €
10g805.00 €
25g1,212.00 €
50g1,894.00 €
Estimated delivery in United States, on Monday 17 Mar 2025
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