CAS 111034-55-0

(3'R,5'S)-3'-Hydroxycotinine Acetate

Description:

(3'R,5'S)-3'-Hydroxycotinine Acetate is a chemical compound derived from cotinine, which is a metabolite of nicotine. This substance is characterized by its specific stereochemistry, indicated by the (3'R,5'S) configuration, which refers to the spatial arrangement of its atoms and affects its biological activity. The presence of a hydroxyl group (-OH) at the 3' position and an acetate group (-OCOCH3) contributes to its solubility and reactivity. This compound is of interest in pharmacological research, particularly in studies related to nicotine metabolism and potential therapeutic applications. Its structural features may influence its interaction with biological targets, such as receptors or enzymes, making it relevant in the context of nicotine addiction and cessation therapies. Additionally, the acetate moiety can enhance its stability and bioavailability. As with many chemical substances, safety and handling precautions are essential due to potential toxicity or reactivity, and its use should be guided by appropriate regulatory standards.

Formula: C₁₂H₁₄N₂O₃

InChI: InChI=1/C12H14N2O3/c1-8(15)17-11-6-10(14(2)12(11)16)9-4-3-5-13-7-9/h3-5,7,10-11H,6H2,1-2H3/t10-,11+/m0/s1

Synonyms:

• (3R-trans)-3-(acetyloxy)-1-methyl-5-(3-pyridinyl)-2-pyrrolidinone
• Hydroxycotinine Acetate
• trans-3'-Hydroxycotinine Acetate

trans-3'-Hydroxy Cotinine Acetate

CAS: 111034-55-0

Stability Hygroscopic
Applications Cotinine derivative. Carcinogen.

Formula: C₁₂H₁₄N₂O₃

Color and Shape: Neat

Molecular weight: 234.25

Ref: TR-H924508

trans-3'-Hydroxy Cotinine-d3 Acetate

Controlled Product

CAS: 111034-55-0

Applications trans-3'-Hydroxy Cotinine-d3 Acetate is an intermediate in the synthesis of trans-3'-Hydroxy Cotinine-d3 (Racemic Mixtures) (H924510), which is useful in organic synthesis.
References Desai, D., et al.: Chem. Res. Toxicol., 3, 47 (1990)

Formula: C₁₂D₃H₁₁N₂O₃

Color and Shape: Neat

Molecular weight: 237.27

Ref: TR-H924509