CAS 111072-31-2

2,3-Bis(2-methoxy-4-nitro-5-sulfophenyl)-5-[(phenylamino)carbonyl]-2H-tetrazolium inner salt sodium salt (1:1)

Description:

2,3-Bis(2-methoxy-4-nitro-5-sulfophenyl)-5-[(phenylamino)carbonyl]-2H-tetrazolium inner salt sodium salt (1:1), commonly referred to as a tetrazolium compound, is a synthetic organic substance characterized by its complex molecular structure, which includes multiple functional groups such as sulfonic acid, nitro, and amine groups. This compound is typically used in biochemical assays, particularly in cell viability and proliferation studies, due to its ability to be reduced by metabolically active cells, leading to a colorimetric change that can be quantitatively measured. It is soluble in water, which enhances its utility in biological applications. The presence of the sulfonic acid groups contributes to its ionic nature, making it a sodium salt, while the nitro and methoxy groups can influence its reactivity and interaction with biological systems. Safety data sheets should be consulted for handling and toxicity information, as with any chemical substance. Overall, this compound serves as a valuable tool in research and diagnostic applications within the fields of biochemistry and molecular biology.

Formula: C₂₂H₁₇N₇O₁₃S₂·Na

InChI: InChI=1S/C22H17N7O13S2.Na/c1-41-17-8-15(28(31)32)19(43(35,36)37)10-13(17)26-24-21(22(30)23-12-6-4-3-5-7-12)25-27(26)14-11-20(44(38,39)40)16(29(33)34)9-18(14)42-2;/h3-11H,1-2H3,(H2-,23,30,35,36,37,38,39,40);

InChI key: InChIKey=FPEHPQATUMDNDY-UHFFFAOYSA-N

SMILES: O(C)C1=C(N2[N+](=NC(C(NC3=CC=CC=C3)=O)=N2)C4=C(OC)C=C(N(=O)=O)C(S(=O)(=O)[O-])=C4)C=C(S(=O)(=O)O)C(N(=O)=O)=C1.[Na]

Synonyms:

• 2,3-Bis(2-methoxy-4-nitro-5-sulfophenyl)-5-[(phenylamino)carbonyl]-2H-tetrazolium inner salt sodium salt (1:1)
• 2,3-Bis-(2-methoxy-4-nitro-5-sulfophenyl)-2H-tetrazolium-5-carboxanilide
• 2H-Tetrazolium, 2,3-bis(2-methoxy-4-nitro-5-sulfophenyl)-5-[(phenylamino)carbonyl]-, inner salt, monosodium salt
• 2H-Tetrazolium, 2,3-bis(2-methoxy-4-nitro-5-sulfophenyl)-5-[(phenylamino)carbonyl]-, inner salt, sodium salt (1:1)
• Sodium 3′-[1-(phenylaminocarbonyl)-3,4-tetrazolium]bis(4-methoxy-6-nitro)benzenesulfonic acid
• XTT
• XTT (tetrazolium derivative)
• XTT sodium salt

m-Tolyl acetate, 97%

CAS: 111072-31-2

Tetrazolium derivative useful in cancer research

Formula: C₂₂H₁₆N₇NaO₁₃S₂

Purity: 97%

Color and Shape: Powder, Yellow

Molecular weight: 673.52

Ref: 02-J61726

2H-​Tetrazolium, 2,​3-​bis(2-​methoxy-​4-​nitro-​5-​sulfophenyl)​-​5-​[(phenylamino)​carbonyl]​-​, inner salt, sodium salt (1:1)

CAS: 111072-31-2

Formula: C₂₂H₁₇N₇NaO₁₃S₂

Purity: 90%

Color and Shape: Solid

Molecular weight: 674.5293

Ref: IN-DA00ILLH

XTT sodium salt

CAS: 111072-31-2

XTT sodium salt

Formula: C₂₂H₁₆N₇O₁₃S₂·Na

Color and Shape: yellow powder

Molecular weight: 673.01452

Ref: 54-BIX1003

XTT sodium salt

CAS: 111072-31-2

Formula: C₂₂H₁₆N₇NaO₁₃S₂

Purity: ≥ 90%

Color and Shape: Yellow or orange-brown powder

Molecular weight: 673.52

Ref: 7W-GC5281

XTT Sodium for cell culture, 90%, Endotoxin (BET) 5.0EU/mg

CAS: 111072-31-2

Formula: C₂₂H₁₆N₇NaO₁₃S₂

Purity: min. 90%

Color and Shape: Yellow, Powder

Molecular weight: 673.52

Ref: SR-18681

XTT Sodium Salt

Controlled Product

CAS: 111072-31-2

Applications XTT Sodium Salt is used in an assay for cell viability and cell proliferation.
References Roehm, N.W., et al.: J. Immunol. Methods. 142, 257-265 (1991); Lu, J.H., et al.: J. Mol. Cell. Cardiol. 29, 1189-1194 (1997);

Formula: C₂₂H₁₆N₇NaO₁₃S₂

Color and Shape: Neat

Molecular weight: 673.521

Ref: TR-X750930

XTT, sodium salt

CAS: 111072-31-2

XTT is a tetrazolium compound that can be used to measure the activity of enzymes. It has been shown to inhibit the growth of tumor cells in vitro and in vivo. XTT can also be used as an antibacterial agent against C. glabrata and as an anthelmintic drug against tapeworms. This compound is not active against other bacteria, such as E. coli or S. aureus, because they are resistant to oxidative injury and have high levels of ABCG2 (ATP-binding cassette G2), which prevents intracellular accumulation of XTT.

Formula: C₂₂H₁₆N₇NaO₁₃S₂

Molecular weight: 673.53 g/mol

Ref: 3D-X-5000

XTT sodium

CAS: 111072-31-2

XTT sodium salt is a tetrazolium salt, which forms water-soluble formazan on bioreduction and has been used to assess cell viability by production of an orange colour.

Formula: C₂₂H₁₇N₇O₁₃S₂•Na

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 674.53 g/mol

Ref: 3D-EX11661