Kiss2 peptide, associated with the CAS number 1111070-93-9, is a neuropeptide that plays a crucial role in the regulation of reproductive functions in various species, including humans. It is derived from the Kiss1 gene and is known for its involvement in the activation of the hypothalamic-pituitary-gonadal (HPG) axis, which is essential for the onset of puberty and reproductive health. The peptide is characterized by its ability to bind to the GPR54 receptor, triggering a cascade of hormonal responses that stimulate the release of gonadotropin-releasing hormone (GnRH). Kiss2 is typically composed of a sequence of amino acids that contribute to its biological activity and stability. It is often studied in the context of reproductive endocrinology and developmental biology, with implications for understanding fertility, sexual maturation, and potential therapeutic applications in reproductive disorders. Overall, Kiss2 peptide is a significant player in the intricate hormonal signaling pathways that govern reproductive physiology.

Kiss2 peptide

1111070-93-9: Kiss2 peptide, associated with the CAS number 1111070-93-9, is a neuropeptide that plays a crucial role in the regulation of reproductive functions in various species, including humans. It is derived from the Kiss1 gene and is known for its involvement in the activation of the hypothalamic-pituitary-gonadal (HPG) axis, which is essential for the onset of puberty and reproductive health. The peptide is characterized by its ability to bind to the GPR54 receptor, triggering a cascade of hormonal responses that stimulate the release of gonadotropin-releasing hormone (GnRH). Kiss2 is typically composed of a sequence of amino acids that contribute to its biological activity and stability. It is often studied in the context of reproductive endocrinology and developmental biology, with implications for understanding fertility, sexual maturation, and potential therapeutic applications in reproductive disorders. Overall, Kiss2 peptide is a significant player in the intricate hormonal signaling pathways that govern reproductive physiology.

<p>Kiss2 peptide functions as a positive regulator of reproductive behavior. In COS-7 cells, it binds to its homologous G-protein coupled receptor Kiss2R (GPR54), activating the PKA and PKC signaling pathways through Gas and Gaq proteins. This enhances the activity of cAMP response element-dependent luciferase (CRE-luc) and serum response element-dependent luciferase (SRE-luc).</p>

CAS 1111070-93-9

Kiss2 peptide

Kiss2 peptide

Ref: TM-TP3536