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CAS 11118-25-5

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thyrocalcitonin rat

Description:
Thyrocalcitonin, also known as calcitonin, is a peptide hormone produced by the parafollicular cells (C cells) of the thyroid gland in rats and other species. The CAS number 11118-25-5 specifically refers to the rat form of this hormone. Calcitonin plays a crucial role in calcium homeostasis by lowering blood calcium levels, primarily through its action on bone and kidney. It inhibits osteoclast activity, which reduces bone resorption, and promotes renal excretion of calcium. The hormone is composed of a chain of amino acids, and its structure is critical for its biological activity. In addition to its physiological roles, calcitonin has been studied for its potential therapeutic applications, particularly in conditions like osteoporosis and Paget's disease. It is also used in research settings to understand calcium metabolism and related disorders. Overall, thyrocalcitonin is an important regulator of calcium levels in the body, with significant implications for both health and disease.
Formula:C148H228N40O46S3
Synonyms:
  • Calcitonin (rat)
  • H-Cys-Gly-Asn-Leu-Ser-Thr-Cys-Met-Leu-Gly-Thr-Tyr-Thr-Gln-Asp-Leu-Asn-Lys-Phe-His-Thr-Phe-Pro-Gln-Thr-Ser-Ile-Gly-Val-Gly-Ala-Pro-NH2 (Disulfide bond)
  • Calcitonin rat, ≥95% (HPLC)
  • Rat calcitonin
  • H-CYS-GLY-ASN-LEU-SER-THR-CYS-MET-LEU-GLY-THR-TYR-THR-GLN-ASP-LEU-ASN-LYS-PHE-HIS-THR-PHE-PRO-GLN-THR-SER-ILE-GLY-VAL-GLY-ALA-PRO-NH2
  • Calcitonin (rat) H-Cys-Gly-Asn-Leu-Ser-Thr-Cys-Met-Leu-Gly-Thr-Tyr-Thr-Gln-Asp-Leu-Asn-Lys-Phe-His-Thr-Phe-Pro-Gln-Thr-Ser-Ile-Gly-Val-Gly-Ala-Pro-NH2 (Disulfide bond)
  • CART (55-76), rat IPIYEKKYGQVPMCDAGEQCAV(Cys14&Cys20 bridge)
  • H-CYS-GLY-ASN-LEU-SER-THR-CYS-MET-LEU-GLY-THR-TYR-THR-GLN-ASP-LEU-ASN-LYS-PHE-HIS-THR-PHE-PRO-GLN-THR-SER-ILE-GLY-VAL-GLY-ALA-PRO-NH2 (DISULFIDE BRIDGE: 1-7)
  • CYS-GLY-ASN-LEU-SER-THR-CYS-MET-LEU-GLY-THR-TYR-THR-GLN-ASP-LEU-ASN-LYS-PHE-HIS-THR-PHE-PRO-GLN-THR-SER-ILE-GLY-VAL-GLY-ALA-PRO-NH2 RAT
  • CGNLSTCMLGTYTQDLNKFHTFPQTSIGVGAP-NH2 (DISULFIDE BRIDGE: 1-7)
  • See more synonyms
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