CAS 111298-82-9

(6R,7R)-7-Amino-3-[[[5-(carboxymethyl)-4-methyl-2-thiazolyl]thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

Description:

The chemical substance known as (6R,7R)-7-Amino-3-[[[5-(carboxymethyl)-4-methyl-2-thiazolyl]thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, with CAS number 111298-82-9, is a complex bicyclic compound featuring a thiazole moiety and multiple functional groups, including amino and carboxylic acid groups. This structure contributes to its potential biological activity, particularly as an antibiotic or antimicrobial agent. The presence of the thiazole ring enhances its reactivity and interaction with biological targets. The stereochemistry indicated by the (6R,7R) configuration suggests specific spatial arrangements that may influence its pharmacological properties and efficacy. Additionally, the compound's solubility and stability can be affected by the carboxymethyl and thioether functionalities, which may also play a role in its mechanism of action. Overall, this compound represents a class of molecules that may exhibit significant therapeutic potential, warranting further investigation into its biological effects and applications in medicinal chemistry.

Formula: C₁₄H₁₅N₃O₅S₃

InChI: InChI=1S/C14H15N3O5S3/c1-5-7(2-8(18)19)25-14(16-5)24-4-6-3-23-12-9(15)11(20)17(12)10(6)13(21)22/h9,12H,2-4,15H2,1H3,(H,18,19)(H,21,22)/t9-,12-/m1/s1

InChI key: InChIKey=ZVSNBXDHZADFDJ-BXKDBHETSA-N

SMILES: C(O)(=O)C=1N2[C@@]([C@H](N)C2=O)(SCC1CSC=3SC(CC(O)=O)=C(C)N3)[H]

Synonyms:

• TACS
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-amino-3-[[[5-(carboxymethyl)-4-methyl-2-thiazolyl]thio]methyl]-8-oxo-, (6R-trans)-
• (6R,7R)-7-Amino-3-[[[5-(carboxymethyl)-4-methyl-2-thiazolyl]thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-amino-3-[[[5-(carboxymethyl)-4-methyl-2-thiazolyl]thio]methyl]-8-oxo-, (6R,7R)-

Cefodizime Impurity 4 HCl

CAS: 111298-82-9

Formula: C₁₄H₁₅N₃O₅S₃·HCl

Color and Shape: Off-White Solid

Molecular weight: 401.48 36.46

Ref: 4Z-C-313009

TACS

Controlled Product

CAS: 111298-82-9

Applications TACS can be used as reactant/reagent for synthesis, antibacterial activity, pharmacokinetics, and acute toxicity of cephalosporin derivatives containing thiomethyl substituted N-heterocycles and thiourea-acetamido groups.
References Chen, M., et al.: U.S. Pat. Appl. Publ., US 20080182836 A1 20080731 (2008)

Formula: C₁₄H₁₅N₃O₅S₃

Color and Shape: Neat

Molecular weight: 401.48

Ref: TR-T004200

TACS

CAS: 111298-82-9

TACS is a medicinal product that has been developed to target cancer cells and induce apoptosis, or programmed cell death. It contains a Chinese protein that has been shown to have anticancer properties in vitro and in vivo. TACS also contains nintedanib, which is a kinase inhibitor that targets the tumor microenvironment and disrupts the cell cycle of cancer cells. This product has been found to be effective against various types of human cancers, including leukemia. The inhibitors present in TACS work by blocking the growth and spread of cancer cells, making it a promising option for those seeking alternative treatments for cancer.

Formula: C₁₄H₁₅N₃O₅S₃

Purity: Min. 95%

Molecular weight: 401.5 g/mol

Ref: 3D-LEA29882

(6R,7R)-7-Amino-3-(((5-(carboxymethyl)-4-methylthiazol-2-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid

CAS: 111298-82-9

Formula: C₁₄H₁₅N₃O₅S₃

Molecular weight: 401.47

Ref: ST-EA-CP-C361001