CAS 1113-59-3

Bromopyruvic acid

Description:

Bromopyruvic acid, with the CAS number 1113-59-3, is a halogenated derivative of pyruvic acid, characterized by the presence of a bromine atom in its molecular structure. This compound typically appears as a colorless to pale yellow liquid and is known for its reactivity due to the electrophilic nature of the bromine atom. It is soluble in water and organic solvents, making it versatile for various chemical applications. Bromopyruvic acid has garnered attention in biochemical research, particularly for its potential role in cancer therapy, as it can inhibit glycolysis and affect metabolic pathways in cancer cells. The compound is also used in organic synthesis and as a reagent in various chemical reactions. However, it is important to handle bromopyruvic acid with care due to its potential toxicity and the need for appropriate safety measures in laboratory settings. Overall, its unique properties and biological implications make it a subject of interest in both chemistry and pharmacology.

Formula: C₃H₃BrO₃

InChI: InChI=1S/C3H3BrO3/c4-1-2(5)3(6)7/h1H2,(H,6,7)

InChI key: InChIKey=PRRZDZJYSJLDBS-UHFFFAOYSA-N

SMILES: C(C(O)=O)(CBr)=O

Synonyms:

• 3-Bromo-2-Oxopropanoic Acid
• 3-Bromo-2-oxo-propionic acid
• 3-Bromopyruvate
• Bromopyruvic acid
• NSC 11731
• NSC 62343
• Propanoic acid, 3-bromo-2-oxo-
• Pyruvic acid, bromo-
• β-Bromopyruvic acid

Bromopyruvic acid, 97%

CAS: 1113-59-3

Bromopyruvic acid is used as an affinity label for cysteine residues and a potential anti-cancer agent. It is involved in the synthesis of imidazo[1,2-a]pyridine-2-carboxylic acids and substituted pyranones. It plays a vital role as a cross-linker between nucleic acids and proteins. It is used as an

Formula: C₃H₃BrO₃

Purity: 97%

Color and Shape: White to pale cream or pale orange, Crystals or powder or crystalline powder and/or lumps

Molecular weight: 166.96

Ref: 02-L00720

Bromopyruvic acid

CAS: 1113-59-3

Formula: C₃H₃BrO₃

Purity: 96%

Color and Shape: Solid

Molecular weight: 166.9581

Ref: IN-DA0035V2

3-Bromopyruvic acid

CAS: 1113-59-3

3-Bromopyruvic acid

Purity: ≥95%

Molecular weight: 166.96g/mol

Ref: 54-BUP18795

3-Bromopyruvic Acid

CAS: 1113-59-3

Formula: C₃H₃BrO₃

Purity: >98.0%(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 166.96

Ref: 3B-B1153

3-Bromopyruvic acid

CAS: 1113-59-3

3-Bromopyruvic acid (Hexokinase II Inhibitor II, 3-BP) is a hexokinase II inhibitor with Ki of 2.4 mM for glycolysis/hexokinase inhibition.

Formula: C₃H₃BrO₃

Purity: 95% - 99.644%

Color and Shape: White To Pale Yellow Crystalline Powder

Molecular weight: 166.96

Ref: TM-T5882

3-Bromo-2-oxopropanoic acid

CAS: 1113-59-3

3-Bromo-2-oxopropanoic acid

Formula: C₃H₃BrO₃

Purity: 96%

Color and Shape: pale cream crystalline powder

Molecular weight: 166.96g/mol

Ref: 54-OR8799

3-Bromopyruvic acid

CAS: 1113-59-3

Formula: C₃H₃BrO₃

Purity: ≥ 95.0%

Color and Shape: White to red or brown crystalline powder

Molecular weight: 166.96

Ref: 7W-GK0949

Bromopyruvic acid

CAS: 1113-59-3

Formula: C₃H₃BrO₃

Purity: 97%

Color and Shape: Solid

Molecular weight: 166.958

Ref: 10-F048861

Bromopyruvic Acid-13C3

Controlled Product

CAS: 1113-59-3

Formula: C₃H₃BrO₃

Color and Shape: Neat

Molecular weight: 169.936

Ref: TR-B686932

Bromopyruvic Acid

Controlled Product

CAS: 1113-59-3

Stability Moisture Sensitive
Applications Bromopyruvic Acid is a synthetic brominated derivative of pyruvic acid. Bromopyruvic Acid maybe a potential treatment for certain types of cancer as it has shown to be effective at eliminating aggressive liver tumors.
References Ko Y.H. et al.: Cancer Lett., 173, 83 (2001); Geschwind J.F. et al.: Cancer Res., 62, 3209 (2002); Ko Y.H. et al.: J. Bioenerg. Biomembr., 44, 163 (2012);

Formula: C₃H₃BrO₃

Color and Shape: Neat

Molecular weight: 166.96

Ref: TR-B686930

3-Bromopyruvic acid

CAS: 1113-59-3

3-Bromopyruvic acid is an analogue of pyruvic acid which is a hexokinase II inhibitor and an effective antitumor agent.

Formula: C₃H₃BrO₃

Molecular weight: 166.96 g/mol

Ref: 3D-B-8960

3-Bromopyruvic acid

CAS: 1113-59-3

3-Bromopyruvic acid is a small molecule that inhibits an enzyme called dextran sulfate reductase. This enzyme is involved in the formation of sulfate in the body and is important for glycolysis, which is the process by which cells break down glucose to produce energy. 3-Bromopyruvic acid inhibits both cancer cells and normal cells, but has a greater effect on cancer cells. This compound also causes caspase-independent cell death, which means that it does not activate pro-apoptotic proteins. It may work by targeting enzymes involved in energy metabolism or by inhibiting DNA polymerase activity.

Formula: C₃H₃BrO₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 166.96 g/mol

Ref: 3D-FB34045