CAS 111300-80-2
:6,6-difluorocholestanol
Description:
6,6-Difluorocholestanol is a fluorinated derivative of cholesterol, characterized by the presence of two fluorine atoms at the 6-position of the steroid nucleus. This modification can influence its physical and chemical properties, such as solubility, melting point, and biological activity. The compound typically exhibits a solid state at room temperature and is likely to be less hydrophobic than its non-fluorinated counterparts due to the electronegative fluorine atoms. Its structure retains the characteristic steroid framework, which includes four fused carbon rings, contributing to its potential interactions with biological membranes and proteins. The introduction of fluorine can enhance metabolic stability and alter the compound's pharmacokinetics, making it of interest in medicinal chemistry and drug design. Additionally, 6,6-difluorocholestanol may serve as a valuable tool in biochemical research, particularly in studies related to cholesterol metabolism and the development of fluorinated pharmaceuticals. As with any chemical substance, proper handling and safety precautions are essential due to potential toxicity and environmental impact.
Formula:C27H46F2O
InChI:InChI=1/C27H46F2O/c1-17(2)7-6-8-18(3)21-9-10-22-20-16-27(28,29)24-15-19(30)11-13-26(24,5)23(20)12-14-25(21,22)4/h17-24,30H,6-16H2,1-5H3/t18-,19+,20+,21-,22+,23+,24+,25-,26-/m1/s1
Synonyms:- (3Beta,5Alpha)-6,6-Difluorocholestan-3-Ol
- 6,6-Difluorocholestanol
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