CAS 11140-99-1: Ristomycin, sulfate (salt)

Description: Ristomycin sulfate, with the CAS number 11140-99-1, is an antibiotic compound derived from the bacterium Amycolatopsis orientalis. It is primarily known for its activity against Gram-positive bacteria, particularly in the treatment of infections caused by staphylococci and streptococci. Ristomycin functions by inhibiting protein synthesis, thereby preventing bacterial growth. The sulfate form enhances its solubility and stability in aqueous solutions, making it suitable for pharmaceutical formulations. This compound is typically administered parenterally and is used in specific clinical settings, often in combination with other antibiotics to enhance efficacy and reduce resistance. Ristomycin may exhibit side effects, including potential nephrotoxicity and ototoxicity, necessitating careful monitoring during treatment. Its use has declined with the advent of newer antibiotics, but it remains a valuable option in certain resistant infections. As with all antibiotics, appropriate susceptibility testing is recommended to ensure its effectiveness against targeted pathogens.

Formula: H₂O₄S·xUnspecified

InChI: InChI=1/C95H110N8O44/c1-30-47(109)18-37-20-49(30)139-50-19-35(9-16-46(50)108)59(97)84(125)102-64-68(113)33-5-11-40(12-6-33)137-52-21-38-22-53(81(52)145-95-83(76(121)72(117)56(143-95)29-134-91-78(123)73(118)67(112)32(3)136-91)147-94-82(75(120)71(116)55(27-105)142-94)146-92-77(122)69(114)48(110)28-133-92)138-41-13-7-34(8-14-41)80(144-57-25-44(96)66(111)31(2)135-57)65-89(130)101-63(90(131)132-4)43-23-39(106)24-51(140-93-79(124)74(119)70(115)54(26-104)141-93)58(43)42-17-36(10-15-45(42)107)60(85(126)103-65)98-87(128)62(38)99-86(127)61(37)100-88(64)129/h5-24,31-32,44,48,54-57,59-80,82-83,91-95,104-124H,25-29,96-97H2,1-4H3,(H,98,128)(H,99,127)(H,100,129)(H,101,130)(H,102,125)(H,103,126)/t31-,32-,44+,48+,54+,55+,56+,57-,59+,60?,61-,62+,63?,64+,65-,66-,67-,68+,69+,70+,71+,72+,73+,74-,75-,76-,77-,78+,79-,80+,82-,83+,91+,92-,93+,94+,95-/m0/s1

Synonyms:

• Ristomycin, sulfate (salt)
• Ristocetin sulfate
• Ristomycin sulfate

Ristocetin.sulfate, Nocardia lurida

CAS: 11140-99-1

M02451 - Ristocetin.sulfate, Nocardia lurida

• Formula: C₉₅H₁₁₂N₈O₄₈S
• Purity: >90%
• Color and Shape: Solid, Crystalline
• Molecular weight: 2166.01

Ristomycin monosulfate

CAS: 11140-99-1

• Formula: C₉₅H₁₁₀N₈O₄₄·H₂SO₄
• Purity: ≥ 98.0%
• Color and Shape: White to light tan powder

Ristocetin sulfate - mixture of A & B

CAS: 11140-99-1

Promotes binding of vWf to glycoproteins on platelets, inducing aggregation

• Formula: C₉₅H₁₁₀N₈O₄₄H₂SO₄
• Purity: Min. 95%
• Color and Shape: White Yellow Powder
• Molecular weight: 2,166 g/mol