CAS 111406-87-2
:Zileuton
Description:
Zileuton is a synthetic compound classified as a leukotriene synthesis inhibitor, primarily used in the management of asthma. It functions by inhibiting the enzyme lipoxygenase, which is crucial in the production of leukotrienes—potent inflammatory mediators that contribute to bronchoconstriction and airway inflammation. Zileuton is typically administered orally and is known for its ability to reduce the frequency of asthma attacks and improve lung function. The substance is characterized by its relatively low solubility in water and is often formulated as a tablet for therapeutic use. Common side effects may include liver enzyme elevation, gastrointestinal disturbances, and headache. Due to its mechanism of action, Zileuton is particularly beneficial for patients who experience asthma symptoms related to allergic triggers. Monitoring liver function is recommended during treatment, as hepatotoxicity can occur. Overall, Zileuton represents a targeted approach to asthma management, focusing on the inflammatory pathways involved in the disease.
Formula:C11H12N2O2S
InChI:InChI=1S/C11H12N2O2S/c1-7(13(15)11(12)14)10-6-8-4-2-3-5-9(8)16-10/h2-7,15H,1H3,(H2,12,14)
InChI key:InChIKey=MWLSOWXNZPKENC-UHFFFAOYSA-N
SMILES:C(N(C(N)=O)O)(C)C1=CC=2C(S1)=CC=CC2
Synonyms:- 1-[1-(1-Benzothiophen-2-yl)ethyl]-1-hydroxyharnstoff
- 1-[1-(1-Benzothiophen-2-yl)ethyl]-1-hydroxyurea
- 1-[1-(1-Benzothiophén-2-Yl)Éthyl]-1-Hydroxyurée
- A 64077
- Abbott 64077
- Griluto-CR
- Leutrol
- N-(1-Benzo[b]thien-2-ylethyl)-N-hydroxyurea
- Urea, N-(1-benzo[b]thien-2-ylethyl)-N-hydroxy-
- Zyflo
- Zileuton
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Found 14 products.
Zileuton
CAS:Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoiFormula:C11H12N2O2SColor and Shape:PowderMolecular weight:236.061951-[1-(1-benzothiophen-2-yl)ethyl]-1-hydroxyurea
CAS:Formula:C11H12N2O2SPurity:97%Color and Shape:SolidMolecular weight:236.2902Zileuton
CAS:Zileuton (A 64077) inhibits 5-lipoxygenase, reduces leukotrienes, aids bronchodilation, lessens mucus/edema, and helps manage asthma symptoms.Formula:C11H12N2O2SPurity:98.72% - 99.43%Color and Shape:Crystalline SolidMolecular weight:236.29Zileuton
CAS:Formula:C11H12N2O2SPurity:>95.0%(T)(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:236.29Zileuton
CAS:Formula:C11H12N2O2SPurity:≥ 98.0% (anhydrous basis)Color and Shape:White to off-white powderMolecular weight:236.29Zileuton
CAS:Controlled Product<p>Applications An inhibitor of 5-lipoxygenase, the initial enzyme in the biosynthesis of leukotrienes from Arachidonic Acid. Used as an antiasthmatic.<br>References Carter, G.W., et al.: J. Pharmacol. Exp. Ther., 256, 929 (1991), Weinblatt, M.E., et al.: J. Rheumatol., 19, 1537 (1992), McGill, K and Busse, W.W.: Lancet, 348, 519 (1996)<br></p>Formula:C11H12N2O2SColor and Shape:NeatMolecular weight:236.29Zileuton- Bio-X ™
CAS:<p>Zileuton is an inhibitor of the 5-lipoxygenase enzyme, thus preventing the leukotrienes LTE4, LDT4, LTB4 and LTC4 from being formed. This in turn reduces inflammation, bronchoconstriction and mucus secretion in the airways. As a result, Zileuton can be used in the treatment and management of asthma and allergic rhinitis. Studies have shown that Zileuton has the potential to reverse dementia-related brain damage.</p>Formula:C11H12N2O2SPurity:(%) Min. 95%Color and Shape:PowderMolecular weight:236.29 g/molZileuton
CAS:<p>Zileuton is an inhibitor of the 5-lipoxygenase enzyme, thus preventing the leukotrienes LTE4, LDT4, LTB4 and LTC4 from being formed. This in turn reduces inflammation, bronchoconstriction and mucus secretion in the airways. As a result Zileuton can be used in the treatment and management of asthma and allergic rhinitis. However patients can experience hepatoxicity or Neuropsychiatric events such as changes in behaviour and sleep disorder, when taking Zileuton as a treatment. Interestingly studies have shown that Zileuton has the potential to reverse dementia-related brain damage.</p>Formula:C11H12N2O2SPurity:Min. 98%Color and Shape:PowderMolecular weight:236.29 g/mol1-(1-(Benzo[b]thiophen-2-yl)ethyl)-1-hydroxyurea
CAS:Formula:C11H12N2O2SPurity:97%Color and Shape:SolidMolecular weight:236.29
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