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CAS 1114544-31-8: Ponatinib hydrochloride

Description:Ponatinib hydrochloride is a small molecule tyrosine kinase inhibitor primarily used in the treatment of certain types of leukemia, particularly chronic myeloid leukemia (CML) and acute lymphoblastic leukemia (ALL). It selectively targets BCR-ABL, including the T315I mutation, which is resistant to many other therapies. The compound is characterized by its ability to inhibit multiple kinases involved in cancer cell proliferation and survival. Ponatinib hydrochloride is typically administered orally and is known for its potent efficacy, although it may also present a risk of serious side effects, including cardiovascular events and hematologic toxicities. The hydrochloride salt form enhances its solubility and stability, facilitating its formulation for therapeutic use. In terms of chemical properties, ponatinib has a complex structure that includes a pyrimidine core and various functional groups that contribute to its biological activity. As with any medication, its use should be closely monitored by healthcare professionals to manage potential adverse effects and ensure optimal therapeutic outcomes.

  • Synonyms:
  • 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide hydrochloride
  • Ponatinib Mono-hydrochloride
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Ponatinib Hydrochloride

CAS:1114544-31-8

Ref: IN-DA009307

1g155.00 €
5g481.00 €
100mg49.00 €
250mg64.00 €
Estimated delivery in United States, on Friday 28 Feb 2025
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Ponatinib Hydrochloride

CAS:1114544-31-8

Ref: TM-T2372L

10mg47.00 €
25mg79.00 €
50mg111.00 €
100mg169.00 €
200mg243.00 €
500mg411.00 €
Estimated delivery in United States, on Monday 3 Mar 2025
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Ponatinib Hydrochloride

CAS:1114544-31-8

Ref: TR-P215740

50mg129.00 €
100mg203.00 €
250mg390.00 €
Estimated delivery in United States, on Monday 10 Mar 2025
discount label

Ponatinib HCl

CAS:1114544-31-8

Ref: 3D-FP32437

5g1,446.00 €
50mg348.00 €
Estimated delivery in United States, on Friday 11 Apr 2025
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