CAS 1114544-31-8
:Ponatinib hydrochloride
Description:
Ponatinib hydrochloride is a small molecule tyrosine kinase inhibitor primarily used in the treatment of certain types of leukemia, particularly chronic myeloid leukemia (CML) and acute lymphoblastic leukemia (ALL). It selectively targets BCR-ABL, including the T315I mutation, which is resistant to many other therapies. The compound is characterized by its ability to inhibit multiple kinases involved in cancer cell proliferation and survival. Ponatinib hydrochloride is typically administered orally and is known for its potent efficacy, although it may also present a risk of serious side effects, including cardiovascular events and hematologic toxicities. The hydrochloride salt form enhances its solubility and stability, facilitating its formulation for therapeutic use. In terms of chemical properties, ponatinib has a complex structure that includes a pyrimidine core and various functional groups that contribute to its biological activity. As with any medication, its use should be closely monitored by healthcare professionals to manage potential adverse effects and ensure optimal therapeutic outcomes.
Formula:C29H28ClF3N6O
Synonyms:- 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide hydrochloride
- Ponatinib Mono-hydrochloride
- AP24534 Mono-hydrochloride
- Ponatinib-HCl
- Ponatinib hydrochloride
- AP24534-HCl
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Found 5 products.
Ponatinib Hydrochloride
CAS:<p>Ponatinib Hydrochloride (AP-24534 Hydrochloride) is a hydrochloride of ponatinib.</p>Formula:C29H28ClF3N6OPurity:99.88%Color and Shape:SolidMolecular weight:569.02Ponatinib Mono-hydrochloride
CAS:Formula:C29H28ClF3N6OPurity:99%Color and Shape:SolidMolecular weight:569.0204Ponatinib HCl
CAS:<p>BCR-ABL1 tyrosine kinase inhibitor</p>Formula:C29H27F3N6O·HClPurity:Min. 95%Molecular weight:569.02 g/mol
