CAS 111490-36-9

Zeniplatin

Description:

Zeniplatin, with the CAS number 111490-36-9, is a platinum-based chemotherapeutic agent that is primarily investigated for its potential use in cancer treatment. It is a derivative of cisplatin, designed to enhance efficacy and reduce side effects associated with traditional platinum compounds. Zeniplatin exhibits characteristics typical of platinum drugs, including the ability to form DNA cross-links, which disrupts cancer cell replication and promotes apoptosis. Its mechanism of action involves binding to DNA, leading to the formation of intrastrand cross-links that inhibit transcription and replication processes. This compound is noted for its improved solubility and bioavailability compared to its predecessors, which may contribute to its therapeutic potential. Additionally, Zeniplatin is being studied for its effectiveness against various types of tumors, including those resistant to other platinum-based therapies. Ongoing research aims to better understand its pharmacokinetics, toxicity profile, and overall clinical efficacy in oncology settings.

Formula: C₁₁H₂₂N₂O₆Pt

InChI: InChI=1/C6H8O4.C5H14N2O2.Pt/c7-4(8)6(5(9)10)2-1-3-6;6-1-5(2-7,3-8)4-9;/h1-3H2,(H,7,8)(H,9,10);8-9H,1-4,6-7H2;

SMILES: C1CC(C1)(C(=O)O)C(=O)O.C(C(CN)(CO)CO)N.[Pt]

Synonyms:

• Zeniplatin [USAN:INN]
• Cl 286558
• Platinum, (2,2-bis(aminomethyl)-1,3-propanediol-N,N')(1,1-cyclobutanedicarboxylato(2-))-, (SP-4-2)-
• Unii-40Zq0A17It
• Zeniplatine
• Zeniplatine [INN-French]
• Zeniplatino
• Zeniplatino [INN-Spanish]
• Zeniplatinum
• Zeniplatinum [INN-Latin]
• cis-(2,2-Bis(aminomethyl)-1,3-propanediol)(1,1-cyclobutanedicarboxylato)platinum
• 2,2-Bis(Aminomethyl)Propane-1,3-Diol
• Cyclobutane-1,1-Dicarboxylic Acid

Zeniplatin

CAS: 111490-36-9

Zeniplatin (Zeniplatinum) is a new cisplatin complex with anticancer activity for the treatment of metastatic melanoma and kidney cancer.

Formula: C₁₁H₂₀N₂O₆Pt

Purity: >99.99%

Color and Shape: Solid

Molecular weight: 471.36

Ref: TM-T35300

Zeniplatin

CAS: 111490-36-9

Zeniplatin

Purity: ≥98%

Molecular weight: 471.36g/mol

Ref: 54-BUP00475

Zeniplatin

CAS: 111490-36-9

Formula: C₁₁H₂₂N₂O₆Pt

Molecular weight: 473.39

Ref: 7W-GP2271