CAS 1115-70-4
:Metformin hydrochloride
Description:
Metformin hydrochloride is an oral antihyperglycemic agent primarily used in the management of type 2 diabetes mellitus. It belongs to the biguanide class of medications and functions by decreasing hepatic glucose production, enhancing insulin sensitivity, and improving peripheral glucose uptake and utilization. The substance appears as a white to off-white crystalline powder, which is soluble in water but has limited solubility in organic solvents. Its chemical formula is C4H11N5·HCl, and it has a molecular weight of approximately 165.63 g/mol. Metformin hydrochloride is typically administered in tablet form and is known for its favorable safety profile, with gastrointestinal side effects being the most common. It is also associated with a low risk of hypoglycemia when used alone. Additionally, research has indicated potential benefits beyond glycemic control, including cardiovascular protection and weight management. As with any medication, it is essential to use metformin under medical supervision, considering contraindications and potential interactions with other drugs.
Formula:C4H11N5·ClH
InChI:InChI=1S/C4H11N5.ClH/c1-9(2)4(7)8-3(5)6;/h1-2H3,(H5,5,6,7,8);1H
InChI key:InChIKey=OETHQSJEHLVLGH-UHFFFAOYSA-N
SMILES:C(NC(=N)N)(N(C)C)=N.Cl
Synonyms:- 1,1-Dimethylbiguanide Hydrochloride
- 3-(Diaminomethylidene)-1,1-Dimethylguanidine Hydrochloride (1:1)
- Apo-Metformin
- Apophage
- Benofomin
- Biguanide, 1,1-dimethyl-, hydrochloride
- Biguanide, 1,1-dimethyl-, monohydrochloride
- Dabex
- Denkaform
- Dextin
- Diabefagos
- Diabetmim
- Diabetmin
- Diabetosan
- Diabex
- Diaformin
- Dialon
- Diformin
- Diformin Retard
- Dimefor
- Fornidd
- Fortamet
- Geamet
- Glifage
- Glucaminol
- Glucofago
- Glucoform
- Glucoformin
- Glucomet
- Glucomin
- Glucomine
- Gluconil
- Glucophage
- Glucophage 850
- Glucophage Forte
- Glucophage Retard
- Glucophage SR
- Glucophage XR
- Glucophage-Mite
- Gludepatic
- Glufor
- Gluformin
- Glumeformin
- Glumetza
- Glumin
- Glumin XR
- Glupermin
- Glyceriphage
- Glyciphage
- Glycon
- Glyformin
- Imidodicarbonimidic diamide, N,N-dimethyl-, hydrochloride (1:1)
- Imidodicarbonimidic diamide, N,N-dimethyl-, monohydrochloride
- La 6023
- Meguan
- Melbin
- Metforal
- Metformin Hydrochloride
- Metgluco
- Metomin
- Miformin
- N,N-Dimethylbiguanide hydrochloride
- N,N-Dimethylbiguanidine monohydrochloride
- N,N-Dimethylbiguanidinium chloride
- N<sup>1</sup>,N<sup>1</sup>-Dimethylbiguanide hydrochloride
- Neodipa
- Obimat-SR
- Orabet
- Riomet
- Siamformet
- See more synonyms
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Metformin Hydrochloride
CAS:Formula:C4H11N5·HClPurity:>98.0%(HPLC)(T)Color and Shape:White to Almost white powder to crystalMolecular weight:165.631,1-Dimethylbiguanide hydrochloride
CAS:1,1-Dimethylbiguanide hydrochloride (HCl), or metformin HCl, 1115-70-4, is the salt form of the biguanide with antineoplastic and antihyperglycemic properties. Learn more.Formula:C4H12ClN5Color and Shape:White, Crystalline powderMolecular weight:165.63METFORMIN HYDROCHLORIDE CRS
CAS:METFORMIN HYDROCHLORIDE CRSFormula:C4H12ClN5Color and Shape:Added ModifiedMolecular weight:165.6246Metformin hydrochloride
CAS:Metformin hydrochlorideFormula:C4H12ClN5Purity:100%Color and Shape:WhiteMolecular weight:165.07812Metformin Hydrochloride
CAS:Non-aromatic imines and their derivatives; salts thereof, nesoiFormula:C4H11N5·HClColor and Shape:White Off-White PowderMolecular weight:129.10145Metformin hydrochloride
CAS:Metformin hydrochloride (1,1-Dimethylbiguanide hydrochloride) is an AMPK activator. Metformin is used in type 2 diabetes research. Cost-effective and quality-assured.Formula:C4H12ClN5Purity:97.53% - 99.99%Color and Shape:White Or Almost White Crystals Solid CrystallineMolecular weight:165.631,1-Dimethylbiguanide hydrochloride
CAS:Formula:C4H12ClN5Purity:97%Color and Shape:SolidMolecular weight:165.6246Metformin hydrochloride
CAS:Metformin hydrochlorideFormula:C4H12ClN5Purity:≥95%Color and Shape:SolidMolecular weight:165.63Metformin hydrochloride, EP grade
CAS:Formula:C4H11N5·HClPurity:98.5 - 101.0 % (dried substance)Color and Shape:White or almost white crystalsMolecular weight:165.62Metformin hydrochloride
CAS:Formula:C4H11N5·HClPurity:(Titration) 98.0 - 102.0 % (dried basis)Color and Shape:White or almost white crystalline powderMolecular weight:165.62Metformin HCl
CAS:Formula:C4H11N5·HClColor and Shape:White To Off-White SolidMolecular weight:129.17 36.461,1-Dimethylbiguanide hydrochloride
CAS:1,1-Dimethylbiguanide hydrochlorideFormula:C4H11N5·ClHPurity:97%Color and Shape:Off-white SolidMolecular weight:165.624571,1-Dimethyl-d6-biguanide HCl(Metformin HCl; N,N-Dimethyldiguanide HCl)
CAS:Purity:99 atom % DColor and Shape:White SolidMolecular weight:171.66Metformin Hydrochloride
CAS:Controlled ProductApplications An oral hypoglycemic agent. Slows electron transport in the oxidation pathway in mitochondria. Has been reported to reverse Lupus symptoms in mice in conjunction with 2-deoxy-d-glucose (D239000). Metformin is a well-known type 2 diabetes treatment. Research shows that metformin may inhibit tumor growth both directly and indirectly. Studies indicate that metformin modulates the biology of aging. Metformin blocks the conversion of select substrates into glucose in a redox-dependent manner.
References Tucker, G.T., et al.: Brit. J. Clin. Pharmacol., 12, 235 (1981), DeFronzo, R.A., et al.: N. Engl. J. Med., 333, 541 (1995); Chem. and Eng. News, page 7, Feb. 23 (2015); Nir Barzilai et al., Cell Metabolism 23: 1060 June 14 (2016); Chem. and Eng. News, page 7, Feb. 23 (2015); Chem. and Eng. News, page 12, July 30 (2018)Formula:C4H11N5·ClHColor and Shape:NeatMolecular weight:165.62Metformin HCl
CAS:1,1-Dimethylbiguanide HydrochlorideFormula:C4H12ClN5Purity:97%Molecular weight:165.62
