CAS 111523-41-2

Enloplatin

Description:

Enloplatin, with the CAS number 111523-41-2, is a platinum-based chemotherapeutic agent primarily used in the treatment of various cancers, including ovarian and lung cancers. It is classified as a second-generation platinum compound, designed to overcome some of the limitations associated with traditional platinum drugs like cisplatin and carboplatin, particularly in terms of toxicity and resistance. Enloplatin exhibits a unique mechanism of action, wherein it forms DNA cross-links, ultimately leading to apoptosis in cancer cells. Its solubility and stability in physiological conditions are enhanced compared to its predecessors, which may contribute to its efficacy and reduced side effects. The compound is typically administered intravenously and is subject to ongoing research to further elucidate its pharmacokinetics, optimal dosing regimens, and potential combinations with other therapeutic agents. As with many chemotherapeutics, monitoring for side effects and patient response is crucial during treatment.

Formula: C₁₃H₂₂N₂O₅Pt

InChI: InChI=1/C7H16N2O.C6H8O4.Pt/c8-5-7(6-9)1-3-10-4-2-7;7-4(8)6(5(9)10)2-1-3-6;/h1-6,8-9H2;1-3H2,(H,7,8)(H,9,10);/q;;+2/p-2

InChI key: InChIKey=ASQRQYODAQUVBR-UHFFFAOYSA-L

SMILES: O=C1C2(C(=O)[O-][Pt+2]3([O-]1)[NH2]CC4(C[NH2]3)CCOCC4)CCC2

Synonyms:

• 1,1-Cyclobutanedicarboxylic acid, platinum complex
• 4H-Pyran-4,4-dimethanamine, tetrahydro-, platinum complex
• Cl 287110
• Enloplatin [USAN:INN]
• Enloplatine
• Enloplatine [INN-French]
• Enloplatino
• Enloplatino [INN-Spanish]
• Enloplatinum
• Enloplatinum [INN-Latin]
• Platinum, (1,1-cyclobutanedicarboxylato(2-))(tetrahydro-4H-pyran-4,4-dimethanamine-N,N')-, (SP-4-2)-
• Platinum, [1,1-cyclobutanedi(carboxylato-κO)(2-)](tetrahydro-4H-pyran-4,4-dimethanamine-κN⁴,κN^4′)-, (SP-4-2)-
• Unii-C7Ht2Io79H
• cis-(1,1-Cyclobutanedicarboxylato)(tetrahydro-4H-pyran-4,4-bis(methylamine))platinum
• platinum(2+) cyclobutane-1,1-dicarboxylate - tetrahydro-2H-pyran-4,4-diyldimethanamine (1:1:1)
• Enloplatin
• Platinum, [1,1-cyclobutanedi(carboxylato-κO)(2-)](tetrahydro-4H-pyran-4,4-dimethanamine-κN4,κN4′)-, (SP-4-2)-
• (SP-4-2)-[1，1-Cyclobumnedicarboxylato(2-)](tetrahydro-4H-pyran-4,4-dimethanamine-N，N’)platinum
• platinum, (1,1-cyclobutanedicarboxylato(2-))(tetrahydro-4h-pyran-4,4-dimethanam (sp-4-2)-ine-n cis-(1,1-cyclobutanedicarboxylato)(tetrahydro-4h-pyran-4,4-bis(methylami ne)) platinum cl 287110 enloplatin

Enloplatin

CAS: 111523-41-2

Enloplatin

Purity: ≥95%

Molecular weight: 481.4g/mol

Ref: 54-BUP08042

Enloplatin

CAS: 111523-41-2

Formula: C₁₃H₂₄N₂O₅Pt

Molecular weight: 483.42

Ref: 7W-GP1429

Enloplatin

CAS: 111523-41-2

Enloplatin is a carboplatin analog that has a partial role in advanced ovarian cancer.

Formula: C₁₃H₂₂N₂O₅Pt

Purity: 97.77% - 99.73%

Color and Shape: Solid

Molecular weight: 481.4

Ref: TM-T68065