CAS 111555-53-4

Naltrindol

Description:

Naltrindol is a synthetic compound that belongs to the class of opioid receptor antagonists. It is primarily characterized by its ability to selectively bind to the mu-opioid receptors, which makes it a subject of interest in the study of pain management and addiction treatment. Naltrindol is known for its potential to mitigate the effects of opioid drugs, thereby reducing the risk of dependency and overdose. The compound exhibits a unique chemical structure that contributes to its pharmacological properties, including its affinity for various opioid receptors. In addition to its antagonistic effects, Naltrindol has been investigated for its role in modulating the central nervous system and its potential therapeutic applications in conditions such as depression and anxiety. Its safety profile and side effects are still under research, making it a compound of interest in pharmacological studies. Overall, Naltrindol represents a significant area of exploration in the development of new treatments for opioid-related disorders.

Formula: C₂₆H₂₆N₂O₃

InChI: InChI=1/C26H26N2O3/c29-19-8-7-15-11-20-26(30)12-17-16-3-1-2-4-18(16)27-22(17)24-25(26,21(15)23(19)31-24)9-10-28(20)13-14-5-6-14/h1-4,7-8,14,20,24,27,29-30H,5-6,9-13H2/t20-,24+,25+,26-/m1/s1

InChI key: InChIKey=WIYUZYBFCWCCQJ-IFKAHUTRSA-N

SMILES: O[C@]12[C@@]34C=5C(O[C@]3(C6=C(C1)C=7C(N6)=CC=CC7)[H])=C(O)C=CC5C[C@]2(N(CC8CC8)CC4)[H]

Synonyms:

• (4bS,8R,8aS,14bR)-7-(Cyclopropylmethyl)-5,6,7,8,14,14b-hexahydro-4,8-methanobenzofuro[2,3-a]pyrido[4,3-b]carbazole-1,8a(9H)-diol
• (4bS,8S,8aS,14bR)-7-(cyclopropylmethyl)-5,6,7,8,14,14b-hexahydro-4,8-methano[1]benzofuro[2,3-a]pyrido[4,3-b]carbazole-1,8a(9H)-diol
• 4,8-Methanobenzofuro[2,3-a]pyrido[4,3-b]carbazole-1,8a(9H)-diol, 7-(cyclopropylmethyl)-5,6,7,8,14,14b-hexahydro-, (4bS,8R,8aS,14bR)-
• 4,8-Methanobenzofuro[2,3-a]pyrido[4,3-b]carbazole-1,8a(9H)-diol, 7-(cyclopropylmethyl)-5,6,7,8,14,14b-hexahydro-, [8R-(4bS*,8α,8aβ,14bβ)]-
• Naltrindole
• Nih 10589
• 17-Cyclopropylmethyl-6,7-dehydro-4,5-epoxy-3,14-dihydroxy-6,7,2',3'-indolomorphinan
• 4,8-Methanobenzofuro(2,3-A)pyrido(4,3-B)carbazole-1,8A(9H)-diol, 7-(cyclopropylmethyl)-5,6,7,8,14,14B-hexahydro-, (8R-(4bs*,8alpha,8abeta,14bbeta))-
• Naltrindol

Naltrindole

CAS: 111555-53-4

Naltrindole is a delta opioid receptor antagonist.

Formula: C₂₆H₂₆N₂O₃

Color and Shape: Solid

Molecular weight: 414.5

Ref: TM-T71433