CAS 111627-26-0

4-Piperidinecarboxylic acid, 1-(phenylsulfonyl)-, ethyl ester

Description:

4-Piperidinecarboxylic acid, 1-(phenylsulfonyl)-, ethyl ester is a chemical compound characterized by its piperidine ring structure, which contributes to its cyclic amine properties. This compound features a carboxylic acid functional group and an ethyl ester moiety, indicating it can participate in various chemical reactions typical of esters and acids. The presence of a phenylsulfonyl group enhances its reactivity and solubility in organic solvents, making it useful in synthetic organic chemistry. It is often utilized in the development of pharmaceuticals and agrochemicals due to its potential biological activity. The compound's molecular structure allows for hydrogen bonding and dipole interactions, influencing its physical properties such as melting point, boiling point, and solubility. Additionally, its specific stereochemistry can affect its biological interactions and efficacy. As with many chemical substances, safety data should be consulted to understand its handling, storage, and potential hazards. Overall, this compound exemplifies the complexity and utility of piperidine derivatives in chemical synthesis and medicinal chemistry.

Formula: C₁₄H₁₉NO₄S

Ethyl 1-(benzenesulfonyl)piperidine-4-carboxylate

CAS: 111627-26-0

Ethyl 1-(benzenesulfonyl)piperidine-4-carboxylate

Purity: ≥95%

Molecular weight: 297.37g/mol

Ref: 54-OR300532

Ethyl 1-(phenylsulfonyl)piperidine-4-carboxylate

CAS: 111627-26-0

Ethyl 1-(phenylsulfonyl)piperidine-4-carboxylate

Purity: 95%

Molecular weight: 297.375g/mol

Ref: 54-OR97811

1-Benzenesulfonyl-piperidine-4-carboxylic acid ethyl ester

CAS: 111627-26-0

1-Benzenesulfonyl-piperidine-4-carboxylic acid ethyl ester is an inhibitor of acetylcholinesterase. It is a white solid that can be synthesized in two steps from commercially available starting materials. Inhibition of this enzyme leads to the accumulation of acetylcholine, which causes increased stimulation of nicotinic and muscarinic receptors. This drug has been shown to have IC50 values that are similar to those of the reference inhibitor donepezil. 1-Benzenesulfonyl-piperidine-4-carboxylic acid ethyl ester also interacts with sulfonyl chlorides, butyrylcholinesterase, and other proteins in a manner similar to donepezil. The molecular docking studies suggest that this compound binds competitively with the active site of acetylcholinesterase.

Formula: C₁₄H₁₉NO₄S

Purity: Min. 95%

Molecular weight: 297.37 g/mol

Ref: 3D-LEA62726