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CAS 111662-64-7

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Fmoc-.gamma.-carboxy-Glu(OtBu)2-OH

Description:
Fmoc-.gamma.-carboxy-Glu(OtBu)2-OH, also known as Fmoc-γ-carboxy-glutamic acid with two tert-butyl ester groups, is a protected amino acid commonly used in peptide synthesis. The Fmoc (9-fluorenylmethoxycarbonyl) group serves as a protective group for the amino functionality, allowing for selective reactions during peptide assembly. The γ-carboxy group is a key feature of this compound, providing additional functionalization that can be utilized in various biochemical applications. The presence of two tert-butyl ester groups enhances the lipophilicity and stability of the molecule, making it suitable for solid-phase peptide synthesis. This compound is typically used in the synthesis of peptides where specific functional groups need to be protected until the desired stage of the synthesis. Its solubility in organic solvents and stability under standard laboratory conditions make it a valuable reagent in organic and medicinal chemistry. Overall, Fmoc-.gamma.-carboxy-Glu(OtBu)2-OH is an important building block in the field of peptide chemistry, facilitating the creation of complex peptide structures.
Formula:C2H35NO8
Synonyms:
  • Fmoc-Gla(OtBu)-OH
  • Fmoc-L-4-carboxyglutamic acid di-tert.butylester
  • Fmoc-Gla(Otbu)2-Oh
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