CAS 1116745-06-2

Duocarmycin DM

Controlled Product

CAS: 1116745-06-2

Duocarmycin DM is an anticancer drug that selectively targets cancer cells and induces apoptosis. It works by binding to the minor groove of DNA and forming a covalent bond with adenine, which leads to DNA damage and ultimately cell death. Duocarmycin DM has been shown to be effective against a variety of human cancer cell lines, including those resistant to other chemotherapeutic agents. This drug also inhibits kinases involved in tumor growth and angiogenesis, making it a promising candidate for cancer therapy. Duocarmycin DM has been studied as an analog to artesunate and chloroquine in Chinese patients with cancer. Inhibitors of this drug have been identified in urine samples from patients receiving treatment, indicating its potential as a therapeutic agent for the treatment of cancer.

Formula: C₂₆H₂₆ClN₃O₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 464 g/mol

Ref: 3D-RUB74506

Duocarmycin DM free base

CAS: 1116745-06-2

Duocarmycin: DNA-binding, alkylating anticancer agent with a curved indole structure, used in ADCs.

Formula: C₂₆H₂₆ClN₃O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 463.96

Ref: TM-T11119