CAS 111721-75-6

2-Bromo-3-fluoroaniline

Description:

2-Bromo-3-fluoroaniline is an organic compound characterized by the presence of both bromine and fluorine substituents on an aniline structure. It features a bromine atom at the second position and a fluorine atom at the third position of the benzene ring, which is attached to an amino group (-NH2) at the first position. This compound is typically a solid at room temperature and may exhibit a pale yellow to off-white color. It is known for its potential applications in pharmaceuticals and agrochemicals due to the reactivity of the halogen substituents, which can participate in various chemical reactions such as nucleophilic substitutions. The presence of both bromine and fluorine can influence the compound's physical properties, including solubility and boiling point, as well as its reactivity. Additionally, 2-Bromo-3-fluoroaniline may be subject to regulations regarding its handling and disposal due to the potential environmental and health impacts associated with halogenated compounds.

Formula: C₆H₅BrFN

InChI: InChI=1S/C6H5BrFN/c7-6-4(8)2-1-3-5(6)9/h1-3H,9H2

InChI key: InChIKey=XZRSXRUYZXBTGD-UHFFFAOYSA-N

SMILES: BrC1=C(F)C=CC=C1N

Synonyms:

• 2-Bromo-3-Fluoro-Phenylamine
• 2-Bromo-3-fluorobenzenamine
• Benzenamine, 2-bromo-3-fluoro-
• 2-Bromo-3-fluoroaniline

2-Bromo-3-fluoroaniline, 97%

CAS: 111721-75-6

2-Bromo-3-fluoroaniline is used as pharmaceutical intermediate. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference

Formula: C₆H₅BrFN

Purity: 97%

Molecular weight: 190.02

Ref: 02-H61687

2-bromo-3-fluoroaniline

CAS: 111721-75-6

Formula: C₆H₅BrFN

Purity: 97%

Color and Shape: Solid

Molecular weight: 190.0130

Ref: IN-DA003GMR

2-Bromo-3-fluoroaniline

CAS: 111721-75-6

2-Bromo-3-fluoroaniline

Formula: C₆H₅BrFN

Purity: 98%

Color and Shape: light beige/grey crystalline needles

Molecular weight: 190.01g/mol

Ref: 54-PC5082

2-Bromo-3-fluoro-aniline

CAS: 111721-75-6

Formula: C₆H₅BrFN

Purity: 97%

Color and Shape: Solid

Molecular weight: 190.015

Ref: 10-F040426

2-Bromo-3-fluoroaniline

CAS: 111721-75-6

2-Bromo-3-fluoroaniline is a reactive and nucleophilic compound that is synthesized by the reaction of aniline with bromine and sodium hydroxide. The drug development of 2-bromo-3-fluoroaniline has been hampered by its toxicity, but it has shown promising results in animal studies for the treatment of cancer. Mechanistic studies have demonstrated that 2-bromo-3-fluoroaniline causes cell death by reacting with DNA. This drug also acts as a prodrug to fluoroacetic acid, which inhibits cell proliferation by inhibiting protein synthesis.

Formula: C₆H₅BrFN

Purity: Min. 95%

Color and Shape: Solid

Molecular weight: 190.01 g/mol

Ref: 3D-FB67928