CAS 111755-37-4
:microcystin-rr from microcystis*aerguinosa
Description:
Microcystin-RR is a potent cyclic peptide toxin produced by the cyanobacterium Microcystis aeruginosa, commonly found in freshwater environments. It is known for its hepatotoxic properties, primarily affecting the liver and posing significant risks to aquatic life and human health. The chemical structure of microcystin-RR consists of a cyclic heptapeptide, which includes unique amino acids such as D-alanine and N-methyl-dehydroalanine, contributing to its stability and toxicity. This compound inhibits protein phosphatases, particularly PP1 and PP2A, leading to disruptions in cellular signaling and promoting cell death. Microcystin-RR is highly soluble in water, which facilitates its bioavailability and accumulation in aquatic organisms. Its presence in water bodies can indicate harmful algal blooms, raising concerns for drinking water safety and ecosystem health. Monitoring and management of microcystin levels are crucial to mitigate its adverse effects on both environmental and public health.
Formula:C49H75N13O12
InChI:InChI=1/C49H75N13O12/c1-26(24-27(2)37(74-8)25-32-14-10-9-11-15-32)18-19-33-28(3)40(64)60-36(46(70)71)20-21-38(63)62(7)31(6)43(67)56-30(5)42(66)59-35(17-13-23-55-49(52)53)45(69)61-39(47(72)73)29(4)41(65)58-34(44(68)57-33)16-12-22-54-48(50)51/h9-11,14-15,18-19,24,27-30,33-37,39H,6,12-13,16-17,20-23,25H2,1-5,7-8H3,(H,56,67)(H,57,68)(H,58,65)(H,59,66)(H,60,64)(H,61,69)(H,70,71)(H,72,73)(H4,50,51,54)(H4,52,53,55)/b19-18+,26-24+/t27-,28-,29-,30+,33-,34-,35+,36+,37-,39+/m0/s1
Synonyms:- Microcystin-RR, Microcystis aeruginosa
- (5R,8R,11R,12S,15S,18S,19S,22R)-8,15-bis{3-[(diaminomethylidene)amino]propyl}-18-[(1E,3E,5S,6S)-6-methoxy-3,5-dimethyl-7-phenylhepta-1,3-dien-1-yl]-1,5,12,19-tetramethyl-2-methylidene-3,6,9,13,16,20,25-heptaoxo-1,4,7,10,14,17,21-heptaazacyclopentacosane-11,22-dicarboxylic acid
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Found 2 products.
Microcystin RR from algae
CAS:Controlled Product<p>Microcystin RR is a cyclic peptide produced by algae, which was shown to have inhibitory effects on the activity of glutathione reductase and xanthine oxidase. Microcystin RR has been found to cause cell lysis in a variety of cells, including human erythrocytes. It also inhibits the activity of several enzymes, such as ATP synthase and succinate dehydrogenase. The toxicological studies show that Microcystin RR is not easily absorbed through the skin and does not cause systemic toxicity or death in mice. It also has a significant effect on the mitochondrial membrane potential in cells, which may be due to its ability to increase reactive oxygen species production.</p>Formula:C49H75N13O12Purity:Min. 95%Molecular weight:1,038.2 g/molRef: 4Z-M-198005
Discontinued product
