CAS 1118-02-1

trimethylsilyl isocyanate

Description:

Trimethylsilyl isocyanate (TMS-IC) is a chemical compound characterized by the presence of a trimethylsilyl group attached to an isocyanate functional group. Its molecular formula is typically represented as C5H11NOSi. This compound is a colorless to pale yellow liquid with a distinctive odor, and it is known for its reactivity, particularly in the presence of moisture, which can lead to hydrolysis and the formation of isocyanic acid and trimethylsilanol. TMS-IC is utilized in organic synthesis, particularly in the derivatization of alcohols and amines, enhancing their volatility and stability for analysis. It is also employed in the preparation of various silicon-containing compounds. Due to its isocyanate functionality, it can be hazardous, necessitating careful handling to avoid exposure, as it may cause irritation to the skin, eyes, and respiratory system. Proper storage in a cool, dry place away from moisture is essential to maintain its stability and reactivity.

Formula: C₄H₉NOSi

InChI: InChI=1/C4H9NOSi/c1-7(2,3)5-4-6/h1-3H3

InChI key: InChIKey=NIZHERJWXFHGGU-UHFFFAOYSA-N

SMILES: N([Si](C)(C)C)=C=O

Synonyms:

• Isocyanatotrimethylsilane
• Isocyanic acid, trimethylsilyl ester
• Orgatix SI 130
• Silane, isocyanatotrimethyl-
• Trimethylisocyanatosilane
• Trimethylsilylisocyanate
• Trimethysilyl isocyanate
• Trimethylsilyl isocyanate
• Trimethylsilyl isocyanate
• TRIMETHYLSILYLISOCYANATE ,75%
• isocyanatotrimethyl-silan
• TRIMETHYLSILYL ISOCYANATE, STAB.

Trimethylsilyl Isocyanate

CAS: 1118-02-1

Formula: C₄H₉NOSi

Purity: >95.0%(GC)

Color and Shape: Colorless to Almost colorless clear liquid

Molecular weight: 115.21

Ref: 3B-T1106

Trimethylsilyl isocyanate, 94%

CAS: 1118-02-1

Trimethylsilyl isocyanate is used in the preparation of 1-unsubstituted 4-(dialkylamino) imidazolin-2-ones. It finds application in the carbamoylation of aromatic hydrocarbons and alcohols. It is also used in the preparation of primary amides from Grignard reagents. Further, it is used in the synthe

Formula: C₄H₉NOSi

Purity: 94%

Color and Shape: Liquid, Clear to turbid colorless

Molecular weight: 115.21

Ref: 02-A12633

isocyanatotrimethylsilane

CAS: 1118-02-1

Formula: C₄H₉NOSi

Purity: 80%

Color and Shape: Liquid

Molecular weight: 115.2059

Ref: IN-DA003V4H

Trimethylsilyl isocyanate

Controlled Product

CAS: 1118-02-1

Formula: C₄H₉NOSi

Color and Shape: Neat

Molecular weight: 115.206

Ref: TR-T798198

Trimethylsilyl isocyanate

CAS: 1118-02-1

Trimethylsilyl isocyanate (TMISC) is a 5-membered heteroaryl. It has been shown to bind to the receptor and shows activity in vitro. TMISC has been reported as a potential drug for bowel disease, congestive heart, and inflammatory bowel disease. TMISC binds to the protein receptor with high affinity, but its binding affinity decreases when it is combined with trifluoroacetic acid or palladium-catalyzed coupling. TMISC can be used to synthesize degarelix acetate, which is an anti-androgen drug that is used in the treatment of prostate cancer.

Formula: C₄H₉NOSi

Purity: Min. 95%

Molecular weight: 115.21 g/mol

Ref: 3D-FT61205