CAS 111810-18-5

2'''-hydroxychlorothricin

Description:

2'''-Hydroxychlorothricin, with the CAS number 111810-18-5, is a chemical compound that belongs to the class of antibiotics known as aminoglycosides. It is characterized by its hydroxyl group, which contributes to its solubility and reactivity. This compound exhibits antibacterial properties, making it effective against a range of Gram-positive and Gram-negative bacteria. The presence of chlorine in its structure enhances its antimicrobial activity. 2'''-Hydroxychlorothricin is typically used in research and has potential applications in treating bacterial infections. Its mechanism of action involves inhibiting protein synthesis in bacteria, which is crucial for their growth and reproduction. As with many antibiotics, the development of resistance is a concern, necessitating careful use and ongoing research into its efficacy and safety. Overall, 2'''-hydroxychlorothricin represents a significant compound in the field of medicinal chemistry, contributing to the arsenal of tools available for combating bacterial infections.

Formula: C₅₀H₆₃ClO₁₇

InChI: InChI=1/C50H63ClO17/c1-23-22-50-28(20-30(23)44(56)57)13-10-8-7-9-12-27-16-17-29-31(49(27,5)48(60)67-42(43(50)55)46(59)68-50)14-11-15-33(29)65-47-40(54)39(53)41(26(4)63-47)66-36-21-35(38(52)25(3)62-36)64-45(58)37-24(2)32(51)18-19-34(37)61-6/h10,13,16-20,23,25-29,31,33,35-36,38-41,47,52-54,59H,7-9,11-12,14-15,21-22H2,1-6H3,(H,56,57)/b13-10-

Synonyms:

• Chlorothricin, 2A-hydroxy-, (2AR)- (9CI)
• 2'''-hydroxychlorothricin
• Antibiotic K818 B
• Chlorothricin, 2'''-hydroxy-
• Chlorothricin, 2(A)-hydroxy-, (2(A)R)-, (9CI)
• Chlorothricin, 2(sup A)-hydroxy-
• 4-[(4-O-{3-O-[(3-chloro-6-methoxy-2-methylphenyl)carbonyl]-2,6-dideoxyhexopyranosyl}-6-deoxyhexopyranosyl)oxy]-18-hydroxy-15,21a-dimethyl-21,22-dioxo-1,2,3,4,4a,6a,7,8,9,10,12a,15,16,21,21a,21b-hexadecahydro-16a,19-methanobenzo[e]naphtho[2,1-m][1,4]dioxacyclopentadecine-14-carboxylic acid

2'''-Hydroxychlorothricin

CAS: 111810-18-5

Hydroxychlorothricin is an antibiotic belonging to the chlorothricin class. This compound is found in Streptomyces K818 and exhibits antitumor properties, potentially extending the survival period of ICR mice with cancer.

Formula: C₅₀H₆₃ClO₁₇

Color and Shape: Solid

Molecular weight: 971.478

Ref: TM-TN10462