CAS 1119-48-8

4-(Methylamino)butyric acid

Description:

4-(Methylamino)butyric acid, also known as gabapentin, is an organic compound characterized by its structure, which includes a butyric acid backbone with a methylamino group attached to the fourth carbon. This compound is a white crystalline solid that is soluble in water and exhibits a moderate pH level. It is classified as an amino acid derivative and is known for its role in the central nervous system, particularly as a medication used to treat neuropathic pain and epilepsy. The presence of the methylamino group enhances its ability to cross the blood-brain barrier, contributing to its pharmacological effects. Additionally, 4-(Methylamino)butyric acid has a relatively low toxicity profile, making it suitable for therapeutic applications. Its chemical properties include the ability to form salts and undergo various reactions typical of amino acids, such as esterification and amidation. Overall, this compound is significant in both medicinal chemistry and pharmacology due to its therapeutic uses and biochemical interactions.

Formula: C₅H₁₁NO₂

InChI: InChI=1S/C5H11NO2/c1-6-4-2-3-5(7)8/h6H,2-4H2,1H3,(H,7,8)

InChI key: InChIKey=AOKCDAVWJLOAHG-UHFFFAOYSA-N

SMILES: C(CCNC)C(O)=O

Synonyms:

• 4-(Methylamino)Butanoate
• 4-(Methylamino)Butanoic Acid
• 4-(N-Methylamino)butanoic acid
• Butanoic acid, 4-(methylamino)-
• Butyric acid, 4-(methylamino)-
• N-Methyl-4-aminobutyric acid
• N-Methyl-GABA
• N-Methyl-γ-aminobutyric acid

4-(Methylamino)butanoic acid

CAS: 1119-48-8

4-(Methylamino)butanoic acid

Formula: C₅H₁₁NO₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 117.148

Ref: 54-OR74164

4-(Methylamino)butanoic acid

CAS: 1119-48-8

Formula: C₅H₁₁NO₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 117.1463

Ref: IN-DA007DDT

N-Methyl-4-aminobutyric acid

CAS: 1119-48-8

N-Methyl-4-aminobutyric acid is a neurotransmitter that is synthesized from glutamic acid. It has inhibitory effects on the central nervous system and is used to treat seizures, muscle spasms, and other neurological disorders. N-Methyl-4-aminobutyric acid is also produced during the hydrolysis of gamma aminobutyric acid (GABA) by hydrochloric acid. The reaction products of these reactions are assayed using an assay based on monoclonal antibodies. N-Methyl-4-aminobutyric acid also inhibits the uptake of GABA in the brain, which may be due to its ability to act as a competitive inhibitor with respect to GABA transporter proteins.

Formula: C₅H₁₁NO₂

Purity: (¹H-Nmr) Min. 95 Area-%

Color and Shape: White Powder

Molecular weight: 117.15 g/mol

Ref: 3D-FM25694

4-(Methylamino)butanoic acid

CAS: 1119-48-8

Formula: C₅H₁₁NO₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 117.148

Ref: 10-F242011

N-Methyl-4-aminobutyric acid

CAS: 1119-48-8

4-(Methylamino)butanoic acid

Formula: C₅H₁₁NO₂

Purity: 98%

Molecular weight: 117.15

Ref: IN-DG160423

N-Methyl-4-aminobutyric Acid

Controlled Product

CAS: 1119-48-8

Stability Hygroscopic
Applications A GABA derivative and hydrolysis product of the industrial solvent, N-methyl-2-pyrrolidinone. Biologically it is a product of nicotine catabolism in bacteria and inhibits L-Carnitine from undergoing β-oxidation in mammals. It is commonly found in skin products to prevent wrinkles.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Wells, D., et al.: J. App. Toxicol., 8, 135 (1988), Virmani, M., et al.: Pharmacol. Res., 33, 19 (1996), Chiribau, C., et al.: J. Bacteriol., 187, 3062 (2005),

Formula: C₅H₁₁NO₂

Color and Shape: Neat

Molecular weight: 117.15

Ref: TR-M285745