CAS 111974-69-7: Quetiapine

Description: Quetiapine is an atypical antipsychotic medication primarily used to treat schizophrenia, bipolar disorder, and major depressive disorder. It functions by modulating various neurotransmitter systems in the brain, particularly by antagonizing dopamine D2 and serotonin 5-HT2A receptors, which helps to alleviate symptoms of psychosis and mood disorders. Quetiapine is characterized by its relatively low affinity for muscarinic receptors, which contributes to its favorable side effect profile compared to older antipsychotics. The substance is typically administered in tablet form and is known for its sedative properties, making it useful in managing acute agitation. Quetiapine has a half-life that allows for once or twice daily dosing, and it undergoes extensive hepatic metabolism, primarily via the cytochrome P450 system. Common side effects may include drowsiness, dizziness, and metabolic changes, such as weight gain. As with any medication, it is essential for patients to be monitored for potential adverse effects and to discuss any concerns with their healthcare provider.

Formula: C₂₁H₂₅N₃O₂S

InChI: InChI=1S/C21H25N3O2S/c25-14-16-26-15-13-23-9-11-24(12-10-23)21-17-5-1-3-7-19(17)27-20-8-4-2-6-18(20)22-21/h1-8,25H,9-16H2

InChI key: InChIKey=URKOMYMAXPYINW-UHFFFAOYSA-N

SMILES: OCCOCCN1CCN(C2=NC=3C=CC=CC3SC=4C=CC=CC42)CC1

Synonyms:

• 11-[4-[2-(2-Hydroxyethoxy)Ethyl]-1-Piperazinyl]Dibenzo[B,F][1,4]Thiazepine
• 2-(2-(4-Dibenzo(b,f)(1,4)thiazepine-11-yl-1-piperazinyl)ethoxy)ethanol
• 2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-ylpiperazin-1-yl)ethoxy]ethanol (2E)-but-2-enedioate (2:1) (salt)
• 2-{2-4-(Dibenzob,F1,4Thiazepin-11-Yl)Piperazin-1-Ylethoxy}Ethanol
• 2-{2-[4-(Dibenzo[b,f][1,4]thiazepin-11-yl)-1-piperazinyl]ethoxy}ethanol
• 2-{2-[4-(Dibenzo[b,f][1,4]thiazepin-11-yl)piperazin-1-yl]ethoxy}ethanol
• 2-{[2-(4-Dibenzo[B,F][1,4]Thiazepin-11-Ylpiperazin-1-Yl)Ethyl]Oxy}Ethanol
• Dibenzo[b,f][1,4]thiazepine, ethanol deriv.
• Ethanol, 2-2-(4-Dibenzob,F1,4Thiazepin-11-Yl-1-Piperazinyl)Ethoxy-
• Ethanol, 2-[2-(4-Dibenzo[B,F][1,4]Thiazepin-11-Yl-1-Piperazinyl)Ethoxy]-
• Ketipinor
• Seronia
• Quetiapine

2-(2-(4-(Dibenzo[b,f][1,4]thiazepin-11-yl)piperazin-1-yl)ethoxy)ethanol

CAS: 111974-69-7

• Formula: C₂₁H₂₅N₃O₂S
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 383.5071

Quetiapine

CAS: 111974-69-7

Quetiapine treats schizophrenia and bipolar I, targeting serotonin, dopamine, and adrenoreceptor subtypes, plus H1 histamine …

• Formula: C₂₁H₂₅N₃O₂S
• Purity: 100% - 99.14%
• Color and Shape: White To Off-White Crystalline Powder
• Molecular weight: 383.51

Quetiapine

CAS: 111974-69-7

• Formula: C₂₁H₂₅N₃O₂S
• Color and Shape: Pale Yellow Solid
• Molecular weight: 383.51

Quetiapine Hemifumarate

CAS: 111974-69-7111974-72-2

• Formula: C₂₁H₂₅N₃O₂SC₄H₄O₄
• Purity: >98.0%(T)(HPLC)
• Color and Shape: White to Almost white powder to crystal
• Molecular weight: 441.55

2-(2-(4-(Dibenzo[b,f][1,4]thiazepin-11-yl)piperazin-1-yl)ethoxy)ethanol

CAS: 111974-69-7

• Purity: 95.0%
• Color and Shape: Solid
• Molecular weight: 383.510009765625

Quetiapine

CAS: 111974-69-7

Stability Very Very Hygroscopic Applications Quetiapine is a dibenzothiazepine antipsychotic commonly used as monotherapy for …

• Formula: C₂₁H₂₅N₃O₂S
• Color and Shape: Off-White To Yellow
• Molecular weight: 383.51

Quetiapine

CAS: 111974-69-7

Quetiapine is a psychotropic drug that belongs to the class of atypical antipsychotics. It is …

• Formula: C₂₁H₂₅N₃O₂S
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 383.51 g/mol