CAS 111974-74-4

Dibenzo[b,f][1,4]thiazepine, 11-(1-piperazinyl)-, hydrochloride (1:2)

Description:

Dibenzo[b,f][1,4]thiazepine, 11-(1-piperazinyl)-, hydrochloride (1:2) is a chemical compound characterized by its complex bicyclic structure, which includes a thiazepine ring fused with two benzene rings. This compound features a piperazine moiety, which contributes to its pharmacological properties. As a hydrochloride salt, it is typically more soluble in water, enhancing its bioavailability for potential therapeutic applications. The compound is known for its interactions with various neurotransmitter systems, making it of interest in medicinal chemistry, particularly in the development of psychotropic medications. Its molecular structure allows for diverse chemical reactivity, which can be exploited in synthetic chemistry. Safety and handling precautions are essential due to the potential biological activity and toxicity associated with similar compounds. Overall, dibenzo[b,f][1,4]thiazepine derivatives are studied for their potential roles in treating psychiatric disorders, but detailed studies on this specific hydrochloride form are necessary to fully understand its properties and applications.

Formula: C₁₇H₁₇N₃S·2ClH

InChI: InChI=1S/C17H17N3S.2ClH/c1-3-7-15-13(5-1)17(20-11-9-18-10-12-20)19-14-6-2-4-8-16(14)21-15;;/h1-8,18H,9-12H2;2*1H

InChI key: InChIKey=PZQCQHZDUIIKFU-UHFFFAOYSA-N

SMILES: C=1(C=2C(SC=3C(N1)=CC=CC3)=CC=CC2)N4CCNCC4.Cl

Synonyms:

• 11-(1-Piperazinyl)-Dibenzo[B,F][1,4]Thiazepine Dihydrochloride
• 11-(1-Piperazinyl)-dibenzo[b,f][1,4]thiazepine,2HCl
• 11-(Piperazin-1-Yl)Dibenzo[B,F][1,4]Thiazepine
• 11-Piperazin-1-Yldibenzo[B,F][1,4]Thiazepine Dihydrochloride
• 11-Piperazin-1-yl-dibenzo[b,f][1,4]thiazepine dihydrochloride
• 11-Piperazine-Dibenzo[B,F][1,4]Thiazepine Hydrochloride
• 11-Piperazinodibenzo[b,f][1,4]thiazepine dihydrochloride
• 11-Piperazynil-Dibenzo[B,F][1,4]Thiazepine Dihydrochloride
• 11-piperazinyl-dibenzo[b,f][1,4]thiazepine 2HCl
• Dbtp
• DibenzoB,F1,4Thiazepine-11-Piperazine2Hcl
• Dibenzo[b,f][1,4]thiazepine, 11-(1-piperazinyl)-, dihydrochloride
• Dibenzo[b,f][1,4]thiazepine, 11-(1-piperazinyl)-, hydrochloride (1:2)

Norquetiapine.HCl, 1mg/ml in Methanol (as free base)

CAS: 111974-74-4

Color and Shape: Single Solution

Ref: LP-QUE-1893-HC-1LM

Quetiapine Related Compound B (11-(Piperazin-1-yl)dibenzo[b,f][1,4]thiazepine dihydrochloride)

CAS: 111974-74-4

Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi

Formula: C₁₇H₁₇N₃S·2HCl

Color and Shape: Off-White Powder

Molecular weight: 295.11432

Ref: 45-1592737

11-Piperazinodibenzo[b,f][1,4]thiazepine DiHCl

CAS: 111974-74-4

Formula: C₁₇H₁₉Cl₂N₃S

Purity: 95%

Color and Shape: Solid

Molecular weight: 368.3239

Ref: IN-DA003AZ3

11-(1-Piperazinyl)-Dibenzo[b,f][1,4]Thiazepine Dihydrochloride

CAS: 111974-74-4

11-(1-Piperazinyl)-Dibenzo[b,f][1,4]Thiazepine Dihydrochloride

Purity: 98%

Molecular weight: 368.33g/mol

Ref: 54-OR1009319

Quetiapine EP Impurity B DiHCl (Quetiapine USP Related Compound B)

CAS: 111974-74-4

Formula: C₁₇H₁₇N₃S·2HCl

Color and Shape: White To Off-White Solid

Molecular weight: 295.40 2*36.46

Ref: 4Z-Q-019

Norquetiapine.HCl

CAS: 111974-74-4

Color and Shape: Neat

Ref: LP-QUE-1893-HC-10

11-(Piperazin-1-yl)dibenzo[b,f][1,4]thiazepine Dihydrochloride

Controlled Product

CAS: 111974-74-4

Formula: C₁₇H₁₇N₃SClH

Color and Shape: Neat

Molecular weight: 368.32

Ref: 86-MM1130.01

11-Piperazin-1-yl-dibenzo[b,f][1,4]thiazepine dihydrochloride

CAS: 111974-74-4

Purity: 97.0%

Color and Shape: Solid

Molecular weight: 368.32000732421875

Ref: 10-F036423

N-Des[2-(2-hydroxyethoxy)ethyl] Quetiapine Dihydrochloride

CAS: 111974-74-4

Impurity Quetiapine EP Impurity B
Applications N-Des[2-(2-hydroxyethoxy)ethyl] Quetiapine Dihydrochloride (Quetiapine EP Impurity B) is a metabolite of Quetiapine, a Benzothiazepine with mixed serotonin and dopamine receptor antagonistic properties used as an antipsychotic.
References DeVane, C., et al.: Clin. Pharmacokinet., 40, 509 (2001), Lin, S., et al.: J. Anal. Toxicol., 28, 443 (2004), Zhou, S., et al.: Curr. Drug Metab., 5, 415 (2004), Grimm, S., et al.: Br. J. Clin. Pharmacol., 61, 58 (2006),

Formula: C₁₇H₁₇N₃S·2ClH

Color and Shape: White To Light Yellow

Molecular weight: 368.32

Ref: TR-D288740

Quetiapine EP Impurity B

CAS: 111974-74-4

Formula: C₁₇H₁₇N₃S(HCl)

Molecular weight: 295.40 : 2(36.46)

Ref: ST-EA-CP-Q1002

N-Des[2-(2-hydroxyethoxy)ethyl] Quetiapine-d4 Dihydrochloride

Controlled Product

CAS: 111974-74-4

Applications A labelled metabolite of Quetiapine (Q510000), a Benzothiazepine with mixed serotonin and dopamine receptor antagonistic properties used as an antipsychotic.
References DeVane, C., et al.: Clin. Pharmacokinet., 40, 509 (2001), Lin, S., et al.: J. Anal. Toxicol., 28, 443 (2004), Zhou, S., et al.: Curr. Drug Metab., 5, 415 (2004), Grimm, S., et al.: Br. J. Clin. Pharmacol., 61, 58 (2006),

Formula: C₁₇H₁₅D₄Cl₂N₃S

Color and Shape: Neat

Molecular weight: 299.427

Ref: TR-D288743

N-Des[2-(2-hydroxyethoxy)ethyl] Quetiapine Dihydrochloride (1 mg/mL in Methanol)

Controlled Product

CAS: 111974-74-4

Formula: C₁₇H₁₇N₃S·2ClH

Color and Shape: Single Solution

Molecular weight: 368.32

Ref: TR-KIT1365

11-(1-Piperazinyl)-dibenzo[b,f][1,4]thiazepine dihydrochloride

CAS: 111974-74-4

11-(1-Piperazinyl)-dibenzo[b,f][1,4]thiazepine dihydrochloride is a useful organic compound for research related to life sciences. The catalog number is T65682 and the CAS number is 111974-74-4.

Formula: C₁₇H₁₉Cl₂N₃S

Color and Shape: Solid

Molecular weight: 368.32

Ref: TM-T65682

11-(1-Piperazinyl)-dibenzo[b,f][1,4]thiazepine dihydrochloride

CAS: 111974-74-4

11-(1-Piperazinyl)-dibenzo[b,f][1,4]thiazepine dihydrochloride is a long-acting drug that has been synthesized as an analog of diazepam. The compound is characterized by high diffraction, interaction and evaporation constants and low molecular weight. It is soluble in water and methanol. 11-(1-Piperazinyl)-dibenzo[b,f][1,4]thiazepine dihydrochloride has been shown to have a constant pharmacokinetic profile and high chemical stability in vivo.

Formula: C₁₇H₁₇N₃S·2HCl

Purity: Min. 98 Area-%

Color and Shape: White Off-White Powder

Molecular weight: 368.32 g/mol

Ref: 3D-FP32447