CAS 1121-30-8

1-hydroxyl-1H-pyridine-2-thione

Description:

1-Hydroxyl-1H-pyridine-2-thione, with the CAS number 1121-30-8, is a heterocyclic compound featuring a pyridine ring substituted with a hydroxyl group and a thione functional group. This compound is characterized by its ability to participate in various chemical reactions due to the presence of both the hydroxyl and thione functionalities, which can act as nucleophiles or ligands in coordination chemistry. It typically exhibits moderate solubility in polar solvents, reflecting the influence of the hydroxyl group on its polarity. The thione group contributes to its reactivity, particularly in forming metal complexes, which can be of interest in coordination chemistry and catalysis. Additionally, 1-hydroxyl-1H-pyridine-2-thione may display biological activity, making it relevant in medicinal chemistry and pharmacology. Its structural features allow for potential applications in various fields, including organic synthesis and materials science. Overall, this compound is notable for its unique combination of functional groups and the resulting chemical properties.

Formula: C₅H₅NOS

InChI: InChI=1/C5H5NOS/c7-6-4-2-1-3-5(6)8/h1-4,7H

InChI key: InChIKey=YBBJKCMMCRQZMA-UHFFFAOYSA-N

SMILES: c1ccn(c(=S)c1)O

Synonyms:

• 1-Hydroxy-1,2-dihydropyridine-2-thione
• 1-Hydroxy-1H-pyridine-2-thione
• 1-Hydroxy-2-(1H)-pyridinethione
• 1-Hydroxy-2-pyridinethione
• 1-Hydroxy-2-thiopyridinone
• 1-hydroxypyridine-2(1H)-thione
• 2-(1H)-Pyridinethione, 1-hydroxy-
• Ai3-60234
• Brn 0109936
• N-Hydroxy-2-thiopyridone
• N-Hydroxypyridine-2(1H)-thione
• N-Hydroxypyridine-2-thione
• Nsc 179790
• Omadine
• Pyrithione
• Sq 2113
• Unii-6Gk82Ec25D
• 1-Hydroxyl-1H-pyridine-2-thione

Pyrithione

CAS: 1121-30-8

Pyrithione (1-hydroxyl-1H-pyridine-2-thione) is a transition metal complex, a zinc ionophore, that causes elevated zinc levels in mammalian cells.

Formula: C₅H₅NOS

Purity: 98.1% - 99.55%

Color and Shape: Solid

Molecular weight: 127.16

Ref: TM-T12593

1-hydroxyl-1H-pyridine-2-thione

CAS: 1121-30-8

Formula: C₅H₅NOS

Purity: 95%

Color and Shape: Solid

Molecular weight: 127.1643

Ref: IN-DA008S6R

Pyrithione

CAS: 1121-30-8

Pyrithione

Purity: ≥95%

Molecular weight: 127.16g/mol

Ref: 54-BUP13580

1-hydroxyl-1H-pyridine-2-thione

CAS: 1121-30-8

Purity: 96%

Molecular weight: 127.1600037

Ref: 10-F866384

1-Hydroxy-2(1H)-pyridinethione

CAS: 1121-30-8

1-Hydroxy-2(1H)-pyridinethione (PYR) is a metal chelate that has been shown to bind to zinc and copper with high affinity. The pyrithione form of this compound is used in the treatment of dandruff, seborrheic dermatitis, and psoriasis. It is also used for the prevention of hair loss and as an adjuvant therapy for cancer. The coordination geometry of PYR is octahedral and its cytosolic concentration is less than 1 μM. Its acute toxicity has been studied in rats, mice, and rabbits, with no deaths occurring up to doses of 2000 mg/kg. In addition to its anti-inflammatory properties, PYR has synergistic effects on cells when combined with sodium salts such as sodium sulfate or sodium chloride.

Formula: C₅H₅NOS

Purity: Min. 95%

Molecular weight: 127.17 g/mol

Ref: 3D-FH175788