CAS 112111-44-1

(S)-(+)-Modafinic acid

Description:

(S)-(+)-Modafinic acid, with the CAS number 112111-44-1, is a chiral compound derived from modafinil, a wakefulness-promoting agent. This substance is characterized by its specific stereochemistry, which contributes to its biological activity. It is typically a white to off-white crystalline solid, soluble in polar solvents such as water and methanol, but less soluble in non-polar solvents. The compound exhibits a moderate melting point and has a relatively stable structure under standard conditions. Its pharmacological properties are linked to its ability to enhance cognitive function and alertness, making it of interest in both medical and research contexts. The presence of a carboxylic acid functional group in its structure is significant for its reactivity and potential interactions with biological systems. As a chiral molecule, it may exhibit different biological activities compared to its enantiomer, highlighting the importance of stereochemistry in drug design and efficacy. Overall, (S)-(+)-Modafinic acid represents a notable compound in the study of cognitive enhancers and related therapeutic applications.

Formula: C₁₅H₁₄O₃S

InChI: InChI=1S/C15H14O3S/c16-14(17)11-19(18)15(12-7-3-1-4-8-12)13-9-5-2-6-10-13/h1-10,15H,11H2,(H,16,17)/t19-/m0/s1

InChI key: InChIKey=QARQPIWTMBRJFX-IBGZPJMESA-N

SMILES: C(S(CC(O)=O)=O)(C1=CC=CC=C1)C2=CC=CC=C2

Synonyms:

• 2-[(S)-(Diphenylmethyl)sulfinyl]acetic acid
• (S)-2-(Benzhydrylsulfinyl)acetic acid
• (S)-(+)-Modafinic acid
• Acetic acid, 2-[(S)-(diphenylmethyl)sulfinyl]-
• Acetic acid, [(S)-(diphenylmethyl)sulfinyl]-

(S)-(+)-Modafinic acid

CAS: 112111-44-1

Formula: C₁₅H₁₄O₃S

Color and Shape: Solid

Molecular weight: 274.3349

Ref: IN-DA007CED

(S)-Modafinil EP Impurity A-d5 ((S)-Modafinil Acid-d5)

CAS: 112111-44-1

Formula: C₁₅H₆D₅O₃S

Color and Shape: White To Off-White Solid

Molecular weight: 279.36

Ref: 4Z-M-3310

(S)-(+)-Modafinil Acid

CAS: 112111-44-1

Formula: C₁₅H₁₆O₃S

Color and Shape: White To Off-White Solid

Molecular weight: 274.34

Ref: 4Z-M-3313

(S)-(+)-Modafinic Acid

CAS: 112111-44-1

Applications (S)-(+)-Modafinic Acid is an intermediate in the synthesis of Modafinil (M482500) related compounds with neuroprotective properties.
References Ternois, J., et al.: Org. Proc. Res. Develop., 12, 614 (2008); Prisinzano, T., et al.: Tetrahedron. Asym., 15, 1053 (2004);

Formula: C₁₅H₁₄O₃S

Color and Shape: Neat

Molecular weight: 274.33

Ref: TR-M482475