CAS 112160-82-4
:PREPRO-ATRIAL NATRIURETIC FACTOR (26-55) (HUMAN)
Description:
Prepro-atrial natriuretic factor (26-55) (human), associated with the CAS number 112160-82-4, is a peptide derived from the precursor protein prepro-atrial natriuretic peptide (pro-ANP). This peptide plays a crucial role in cardiovascular homeostasis, primarily by regulating blood pressure and fluid balance. It is produced in the atria of the heart and is released in response to atrial stretch, typically due to increased blood volume. The active form of this peptide acts on the kidneys to promote natriuresis, which is the excretion of sodium in urine, and it also inhibits the renin-angiotensin-aldosterone system, leading to vasodilation and decreased blood pressure. Characteristically, this peptide is hydrophilic, allowing it to circulate freely in the bloodstream, and it exhibits a relatively short half-life due to rapid degradation by peptidases. Its biological activity is significant in the context of heart failure and hypertension, making it a subject of interest in cardiovascular research and potential therapeutic applications.
Formula:C152H236N38O51S3
Synonyms:- Prepro-Hanf (26-55) Cardiodilatin-Related Peptide (Human)
- Prepro-Hanf Fragment 26-55, Human
- Prepro-Anf (26-55), Human
- Prepro-Atrial Natriuretic Peptide, Fragment 26-55 Human
- H-Asn-Pro-Met-Tyr-Asn-Ala-Val-Ser-Asn-Ala-Asp-Leu-Met-Asp-Phe-Lys-Asn-Leu-Leu-Asp-His-Leu-Glu-Glu-Lys-Met-Pro-Leu-Glu-Asp-Oh
- Asn-Pro-Met-Tyr-Asn-Ala-Val-Ser-Asn-Ala-Asp-Leu-Met-Asp-Phe-Lys-Asn-Leu-Leu-Asp-His-Leu-Glu-Glu-Lys-Met-Pro-Leu-Glu-Asp
- Prepro--Atrial Natriuretic Peptide, Frag
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Found 2 products.
Prepro-Atrial Natriuretic Factor (26-55) (human)
CAS:Prepro-atrial natriuretic factor (26-55) (human) (NT-pro-ANP (1-30)) is one of four peptide hormones derived from the atrial natriuretic prohormone. It is also known as long acting natriuretic peptide. The peptide has potent vasodilatory properties equal to atrial natriuretic factor. Vasodilation is associated with a 4-5 fold increase in cyclic GMP levels due to activation of particulate guanylate cyclase activity. Like prepro-atrial natriuretic factor (56-92) and kaliuretic peptide it is present in higher concentration in individuals with congestive heart failure. It causes the maximal increase in prostaglandin E2 (PGE2) levels of the three peptides. The known increase in PGE2 in chronic heart failure may be in part secondary to these peptides.Formula:C152H236N38O51S3Color and Shape:White PowderMolecular weight:3507.97Prepro-Atrial Natriuretic Factor (26-55) (human)
CAS:<p>Please enquire for more information about Prepro-Atrial Natriuretic Factor (26-55) (human) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Formula:C152H236N38O51S3Purity:Min. 95%Molecular weight:3,507.92 g/mol


