CAS 112188-16-6

GADOTERIDOL RELATED COMPOUND B (50 MG) (1,4,7,10-TETRAAZACYCLODODECANE-1,4,7-TRIACETIC ACID, MONOGADOLINIUM SALT)

Description:

Gadoteridol related compound B, also known as 1,4,7,10-tetraazacyclododecane-1,4,7-triacetic acid monogadolinium salt, is a gadolinium-based contrast agent primarily used in magnetic resonance imaging (MRI). This compound features a tetraazacyclododecane backbone, which provides a stable chelation environment for the gadolinium ion, enhancing its solubility and reducing toxicity. The triacetic acid moiety facilitates the binding of the gadolinium ion, allowing for effective imaging contrast due to the paramagnetic properties of gadolinium. The compound is characterized by its high stability, low toxicity, and ability to improve the visibility of vascular structures and lesions during MRI scans. It is essential for medical applications to ensure that the compound is administered in appropriate doses to minimize potential side effects, such as nephrotoxicity, particularly in patients with pre-existing kidney conditions. Overall, gadoteridol related compound B is a crucial tool in diagnostic imaging, aiding in the accurate assessment of various medical conditions.

Formula: C₁₄H₂₂GdN₄O₆

InChI: InChI=1/C14H25N4O6.Gd/c19-12(20)9-16-3-1-15-2-4-17(10-13(21)22)6-8-18(7-5-16)11-14(23)24;/h1-11H2,(H,19,20)(H,21,22)(H,23,24);/q-1;+3/p-3

SMILES: C1CN(CCN(CCN(CC[N-]1)CC(=O)O)CC(=O)O)CC(=O)O.[Gd]

Synonyms:

• Gadolinium, (1,4,7,10-tetraazacyclododecane-1,4,7-triacetato(3-)-N1,N4,N7,N10,O1,O4,O7)-
• Gadolinium 1,4,7-triscarboxymethyl-1,4,7,10-tetraazacyclododecane
• Gd(DO3A)
• Gd-DO 3A
• 1,4,7,10-Tetraazacyclododecane-1,4,7-triacetic acid, gadolinium complex
• Gadolinium, (1,4,7,10-tetraazacyclododecane-1,4,7-triacetato(3-)-kappaN1, kappaN4,kappaN7,kappaN10,kappaO1,kappaO4,kappaO7)-
• 2-[4,10-Bis(2-Oxido-2-Oxo-Ethyl)-1,4,10-Triaza-7-Azanidacyclododec-1-Yl]Acetate
• Gadolinium(+3) Cation
• gadolinium(III) 2,2',2''-(1,4,7,10-tetraazacyclododecane-1,4,7-triyl)triacetate
• Gadoteridol Related CoMpound B
• gadolinium(III) 1,4,7,10-tetraazacyclododecane-1,4,7-triacetic acid
• 1,4,7,10-Tetraazacyclododecane-1,4,7-triacetic acid, gadolinium complex (Gadobutrol Impurity)
• Gadobutrol Impurity 100
• Gadoteridol Related Compound B (50 mg) (1,4,7,10-Tetraazacyclododecane-1,4,7-triacetic acid, monogadolinium salt)
• 2-[4,7-bis(carboxylatomethyl)-1,4,7,10-tetrazacyclododec-1-yl]acetate:gadolinium(3+)
• Gadolinium alcohol impurity C
• GADOTERIDOL RELATED COMPOUND B (50 MG) (1,4,7,10-TETRAAZACYCLODODECANE-1,4,7-TRIACETIC ACID, MONOGADOLINIUM SALT)
• Gadolinium, [1,4,7,10-tetraazacyclododecane-1,4,7-triacetato(3-)-kN1,kN4,kN7,kN10,kO1,kO4,kO7]-
• Gadobutrol EP Impurity C (Gadoteridol USP Related Compound B)
• Gadoteridol Related Compound B (1,4,7,10-Tetraazacyclododecane-1,4,7-triacetic acid, monogadolinium (1287653)
• Des(2-Hydroxypropyl) Gadoteridol

Gadobutrol EP Impurity C (Gadoteridol USP Related Compound B, Gd-DO3A)

CAS: 112188-16-6

Formula: C₁₄H₂₃GdN₄O₆

Molecular weight: 500.61

Ref: 4Z-G-317

Des(2-hydroxypropyl) gadoteridol

CAS: 112188-16-6

Formula: C₁₄H₂₃GdN₄O₆

Molecular weight: 500.61

Ref: 7W-GX1699

Des(2-Hydroxypropyl) Gadoteridol

Controlled Product

CAS: 112188-16-6

Stability Hygroscopic
Applications Des(2-hydroxypropyl) Gadoteridol is a contrast imaging agent metabolite from Gadoteridol (G125900), used as an MRI contrast chelating agent.
References Filippi, M. et al.: Chem. Comm., 50, 3453 (2014); Ferrauto, G. et al.: J. Am. Chem. Soc., 136, 638 (2014);

Formula: C₁₄H₂₃GdN₄O₆

Color and Shape: Neat

Molecular weight: 500.61

Ref: TR-D290340

Gadobutrol EP Impurity C

CAS: 112188-16-6

Formula: C₁₄H₂₃GdN₄O₆

Molecular weight: 500.6

Ref: ST-EA-CP-G39003