CAS 1122-44-7

6-Amino-5-iodo-2(1H)-pyrimidinone

Description:

6-Amino-5-iodo-2(1H)-pyrimidinone is a heterocyclic organic compound characterized by its pyrimidine ring structure, which includes an amino group and an iodine substituent. The presence of the amino group at the 6-position and the iodine atom at the 5-position contributes to its reactivity and potential applications in medicinal chemistry. This compound is typically a solid at room temperature and may exhibit moderate solubility in polar solvents due to the presence of the amino group, which can engage in hydrogen bonding. Its molecular structure suggests potential biological activity, making it of interest in the development of pharmaceuticals, particularly in the field of antiviral or anticancer agents. The iodine atom can also enhance the compound's lipophilicity, influencing its pharmacokinetic properties. As with many halogenated compounds, care should be taken regarding its handling and disposal due to potential environmental and health impacts. Overall, 6-Amino-5-iodo-2(1H)-pyrimidinone represents a valuable scaffold for further chemical modifications and biological evaluations.

Formula: C₄H₄IN₃O

InChI: InChI=1S/C4H4IN3O/c5-2-1-7-4(9)8-3(2)6/h1H,(H3,6,7,8,9)

InChI key: InChIKey=UFVWJVAMULFOMC-UHFFFAOYSA-N

SMILES: NC1=C(I)C=NC(=O)N1

Synonyms:

• 2(1H)-Pyrimidinone, 4-amino-5-iodo-
• 2(1H)-Pyrimidinone, 6-amino-5-iodo-
• 4-Amino-5-iodo-2(1H)-pyrimidinone
• 6-Amino-5-iodo-2(1H)-pyrimidinone
• 6-amino-5-iodopyrimidin-2(1H)-one
• Cytosine, 5-iodo-
• 5-Iodocytosine

5-IODOCYTOSINE

CAS: 1122-44-7

Formula: C₄H₄IN₃O

Purity: 98%

Color and Shape: Solid

Molecular weight: 236.9985

Ref: IN-DA003MTA

4-Amino-5-iodo-1H-pyrimidin-2-one

CAS: 1122-44-7

4-Amino-5-iodo-1H-pyrimidin-2-one

Purity: 98%

Color and Shape: Solid

Molecular weight: 237.00g/mol

Ref: 54-OR54491

5-Iodocytosine

CAS: 1122-44-7

Formula: C₄H₄IN₃O

Molecular weight: 237.00

Ref: 7W-GK4403

5-Iodocytosine

CAS: 1122-44-7

5-Iodocytosine is a Heterocyclic compound-pyrimidine, intermediate and building block, halo-.

Formula: C₄H₄IN₃O

Color and Shape: Solid

Molecular weight: 237

Ref: TM-TNU0629

4-amino-5-iodopyrimidin-2(1H)-one

CAS: 1122-44-7

Formula: C₄H₄IN₃O

Purity: 98%

Color and Shape: Solid, White powder

Molecular weight: 237

Ref: 10-F373671

5-Iodocytosine

CAS: 1122-44-7

5-Iodocytosine (5-IC) is an analog of cytosine that can be used as a precursor for the synthesis of thymine. 5-IC has been shown to cross-couple with DNA, which may contribute to its antiviral potency. 5-IC is also a potent inhibitor of dna replication and herpes simplex virus. The biochemical properties of 5-IC have been extensively studied, including its ability to react with hydrochloric acid to form the corresponding tautomers. The hydrolysis rate increases at higher pH values and decreases at lower pH values. Bioconjugate chemistry has been applied to synthesize a bioconjugated prodrug of 5-IC for cancer treatment.

Formula: C₄H₄IN₃O

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 237 g/mol

Ref: 3D-FI08021